Results 131 to 140 of about 778,750 (285)

Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle

open access: yes, 2016
Objective: The development of skeletal muscle insulin resistance is an early physiological defect, yet the intracellular mechanisms accounting for this metabolic defect remained unresolved.
Hoffman, NJ (15694352)   +18 more
core   +1 more source

Fasting-induced glucose intolerance is not impacted by the addition of daily exercise: A randomized crossover study. [PDF]

open access: yesJ Physiol
Bouck T   +12 more
europepmc   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

open access: yesBritish Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė   +5 more
wiley   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

open access: yesBritish Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral   +3 more
wiley   +1 more source

Nr4a3 deficiency disrupts MEK1-ERK1/2-Drp1 signaling, driving adiposity and glucose intolerance in male mice. [PDF]

open access: yesAm J Physiol Endocrinol Metab
Ellsworth PN   +15 more
europepmc   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton   +4 more
wiley   +1 more source

Impaired Hepatic Glucose Metabolism Is Associated With Glucose Intolerance in Mice Carrying α<sub>2</sub> Isoform Na,K-ATPase Mutation. [PDF]

open access: yesActa Physiol (Oxf)
Staehr C   +11 more
europepmc   +1 more source

Tetrahydrofurfuryl Methacrylate and Isobornyl Acrylate: Possible New Sensitisers in Hearing Aid Ear Moulds

open access: yesContact Dermatitis, EarlyView.
A case series of eight patients with allergic otitis externa from contact allergy to hearing aid ear moulds is presented. All were patch test positive to tetrahydrofurfuryl methacrylate and three to isobornyl acrylate. It is postulated that these are likely relevant allergens present in such devices. ABSTRACT Background Allergic contact dermatitis from
Norbertus A. Ipenburg   +2 more
wiley   +1 more source

Clinical Effect Analysis of Spinal Cord Electrical Stimulator Implantation for Diabetic Foot

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective To investigate the clinical effect of spinal cord electrical stimulator implantation in the treatment of diabetic foot (DF). Materials and Methods We recruited 19 patients with DF who were admitted to Shengjing Hospital of China Medical University between January 2018 and May 2020.
Peng‐Bo Zhou, Min Bao
wiley   +1 more source

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