Results 151 to 160 of about 111,943 (300)

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Therapeutic potential of a Bax inhibitor‐1/TMBIM6 antagonist (BIA) and its analogues in Aspergillus fumigatus‐induced asthma via dual targeting of AKT and epithelial‐derived inflammatory cytokines

British Journal of Pharmacology, EarlyView.
Background and Purpose Aspergillus fumigatus (A. fumigatus) exposure causes of severe allergic asthma, characterized by airway inflammation and epithelial dysfunction. TMBIM6 (Bax inhibitor‐1) has been implicated in airway epithelial stress responses and AKT signalling.
Young‐Jin Yu, Ahsan Ullah, Jisun Kim, Mehedi Hasan Bappi, Yerim Heo, Jin Hee Ahn, Hyun‐Kyoung Kim, Han‐Jung Chae   +7 more
wiley   +1 more source

Maternal Obesity Programs Glucose Intolerance in Pregnant Female Offspring. [PDF]

Diabetes
Qiao L, Lu C, Saget S, Shao J.
europepmc   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Gestational Glucose Intolerance and Risk of Obesity in Childhood and Adolescence. [PDF]

J Clin Endocrinol Metab
Maya J, Schulte CCM, Hsu S, James K, Thaweethai T, Pant D, Hivert MF, Powe CE.   +7 more
europepmc   +1 more source

Tetrahydrofurfuryl Methacrylate and Isobornyl Acrylate: Possible New Sensitisers in Hearing Aid Ear Moulds

Contact Dermatitis, EarlyView.
A case series of eight patients with allergic otitis externa from contact allergy to hearing aid ear moulds is presented. All were patch test positive to tetrahydrofurfuryl methacrylate and three to isobornyl acrylate. It is postulated that these are likely relevant allergens present in such devices. ABSTRACT Background Allergic contact dermatitis from
Norbertus A. Ipenburg, Anton C. de Groot, Thomas Rustemeyer   +2 more
wiley   +1 more source

Clinical Effect Analysis of Spinal Cord Electrical Stimulator Implantation for Diabetic Foot

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective To investigate the clinical effect of spinal cord electrical stimulator implantation in the treatment of diabetic foot (DF). Materials and Methods We recruited 19 patients with DF who were admitted to Shengjing Hospital of China Medical University between January 2018 and May 2020.
Peng‐Bo Zhou, Min Bao
wiley   +1 more source

CD59 drives diet-induced obesity and glucose intolerance, insulin resistance, and metabolic dysfunction-associated steatotic liver disease. [PDF]

NPJ Metab Health Dis
Zeibak M, Karbian N, Riahi Y, Baraghithy S, Ahmad L, Tabib A, Abromovitz I, Agranovitz B, Benyamini H, Gottlieb E, Tam J, Dor Y, Leibowitz G, Mevorach D.   +13 more
europepmc   +1 more source

Consensus‐based Guideline on tinea capitis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The consensus‐based guideline developed under the auspices of the German Dermatological Society (DDG) is intended to provide physicians with a structured framework for clinical decision‐making in the management of patients with tinea capitis and to contribute to improved diagnostic accuracy, treatment adherence, and prevention. Tinea capitis is
Peter Mayser, Dietrich Abeck, Philipp P. Bosshard, Jochen Brasch, Georg Daeschlein, Isaak Effendy, Yvonne Gräser, Peter Höger, Julia Huynh, Maria Kinberger, Annette Kolb‐Mäurer, Katharina Antonia Langen, Bartosz Malisiewicz, Alexander Nast, Hagen Ott, Christin Pelzer, Dieter Reinel, Martin Schaller, Silke Uhrlaß, Pietro Nenoff   +19 more
wiley   +1 more source

Psychosocial aspects of early detection in type 1 diabetes: Language matters, decision making and support needs

Diabetic Medicine, EarlyView.
Abstract Aim The potential implementation of early type 1 diabetes (T1D) detection pathways, encompassing autoantibody screening and longitudinal monitoring, raises important psychosocial considerations for ethical, person‐centred care. This review summarises evidence on the psychosocial impact of early T1D detection, identifying key evidence gaps and ...
Maartje de Wit, Laura Yvonne Klinker, Belinda Moore, Anna Boggiss, Lucía Feito Allonca, Mariam Asaad, Keely Bebbington, Bryan Cleal, Sasja Huisman, Per Winterdijk, Henk Jan Aanstoot, Christine Fransman, Elizabeth Holmes‐Truscott, Norbert Hermanns, Giesje Nefs   +14 more
wiley   +1 more source