Results 181 to 190 of about 778,750 (285)

Continuous glucose monitoring detects spontaneous reactive and fasting hypoglycaemia in cystic fibrosis adults without diabetes

open access: yesInternal Medicine Journal, EarlyView.
Abstract People with cystic fibrosis (pwCF) experience a spectrum of glucose disorders. Spontaneous hypoglycaemia is a unique entity affecting pwCF and can be an incidental finding on biochemistry. Our prospective, single‐arm pilot study of eight pwCF without confirmed diabetes and incidental biochemical hypoglycaemia found 62.5% demonstrated fasting ...
Shanal Kumar   +3 more
wiley   +1 more source

MyD88‐Family Adaptors: Compartmentalised Signalling and Non‐Immune Functions

open access: yesImmunology, EarlyView.
MyD88‐family adaptors coordinate receptor‐ and compartment‐specific innate immune signalling across plasma membrane and endosomal pathways. At the plasma membrane, TIRAP/MAL supports MyD88‐dependent signalling downstream of TLR2 and TLR4, whereas endosomal TLR7, TLR8 and TLR9 recruit MyD88 directly.
Seshu Vardhan Pothabathula   +6 more
wiley   +1 more source

Heat shock protein 72 attenuates atherosclerosis in apolipoprotein E‐deficient mice

open access: yesJournal of Diabetes Investigation, EarlyView.
Heat shock (HS) + mild electrical stimulation (MES)‐induced heat shock protein (HSP)72 expression prevents atherogenesis in HSP72+/+/ApoE−/− mice. HS + MES‐induced HSP72 expression reduces macrophage infiltration, oxidative stress, JNK activity, and MCP‐1 expression, and alters macrophage polarity from M1 to M2.
Rintaro Yoshizumi   +12 more
wiley   +1 more source

Cathepsin K: a novel association with glucose intolerance, insulin resistance, and subclinical atherosclerosis in T2DM. [PDF]

open access: yesJ Transl Med
Averta C   +13 more
europepmc   +1 more source

Role of glucagon in metabolic diseases

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Currently, diabetes is defined as “a chronic hyperglycemic state resulting from the absolute or relative insufficiency of insulin action,” emphasizing its characterization as an insulin‐related disease. However, glucagon dysregulation should also play a critical role in the pathophysiology of type 2 diabetes.
Tadahiro Kitamura   +2 more
wiley   +1 more source

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