Results 51 to 60 of about 2,165,842 (306)
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Central carbon metabolism of the biocontrol yeast Pichia anomala [PDF]
, 2004 The biocontrol yeast Pichia anomala prevents mould damage of moist cereal grain during malfunctioning airtight storage but it can also spoil food and feed. This thesis focuses on the physiology and metabolism of P.
Fredlund, Elisabeth
core +1 more source
Biology of Sex DifferencesBackground The age-specific magnitude of the impact of hormones on aging and the role of hormone replacement therapy (HRT) remain unclear. Methods We used data from UK Biobank participants for our analysis.
Yicheng Ma +6 more
doaj +1 more source
Genes and DiseasesMetabolic dysfunction-associated steatotic liver disease (MASLD) is defined by excessive hepatic lipid accumulation. This study evaluated the therapeutic effects and molecular mechanisms of tirzepatide, a dual GIP and GLP-1 receptor agonist, in treating ...
Yun Li +3 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
, 2007 The present study was undertaken to determine the main metabolic secretory signals generated by the mitochondrial substrate MeS (methyl succinate) compared with glucose in mouse and rat islets and to understand the differences.
Schultz, Vera +10 more
core +1 more source
Alzheimer’s Research & TherapyBackground The location of white matter hyperintensities (WMH) is crucial for cognitive impairment. We sought to identify tract-based strategic locations of WMH that are associated with cognitive impairment across the cognitive spectrum from low ...
Chunyan Li +18 more
doaj +1 more source
Liver glucose metabolism in humans [PDF]
Bioscience Reports, 2016 Information about normal hepatic glucose metabolism may help to understand pathogenic mechanisms underlying obesity and diabetes mellitus. In addition, liver glucose metabolism is involved in glycosylation reactions and connected with fatty acid metabolism.
Adeva-Andany, María M. +4 more
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Proteomics identifies complement protein signatures in patients with primary biliary cholangitis
European Journal of Medical ResearchPrimary biliary cholangitis (PBC) is a chronic autoimmune liver disease lacking reliable biomarkers for diagnosis or prognosis. To identify plasma complement biomarkers that improve diagnosis and prognosis of PBC.
Xiaolin Ma +8 more
doaj +1 more source