Results 31 to 40 of about 2,165,842 (306)

FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway

FEBS Open Bio
Previous studies have suggested that women with higher follicle‐stimulating hormone (FSH) levels have a greater incidence of osteoarthritis (OA) compared to women with lower FSH despite normal estrogen levels.
Yu Chen, Na Xu, Wen‐wen Zhang, Yan Wang, Tong Su, Yan‐man Zhou, Jin Xu   +6 more
doaj   +1 more source

Metabolic Fluxes and Stoichiometry of Glucose Metabolism [PDF]

Biophysical Journal, 2008
I would like to comment on a recent article by Bertram et al. titled “Interaction of Glycolysis and Mitochondrial Respiration in Metabolic Oscillations of Pancreatic Islets”(1xInteraction of glycolysis and mitochondrial respiration in metabolic oscillations of pancreatic islets.
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Chemotherapy effects on brain glucose metabolism at rest [PDF]

, 2011
Background: A growing number of studies reports that chemotherapy may impair brain functions inducing cognitive changes which can persist in a subset of cancer survivors.
Riccardo Torta, Elisabetta Geda, Bruno Baudino, Katiuscia Sacco, Gianni Bisi, Federico D'Agata, Giancarlo Castellano, Laura Orsi, Simona Cauda, Rita Ardito, Lorys Castelli, Matteo Manfredi, Paola Caroppo, Antonella Parente, Franco Cauda   +14 more
core  

Effect of different NADH oxidase levels on glucose metabolism by Lactococus lactis : kinetics of intracellular metabolite pools determined by in vivo nuclear magnetic resonance [PDF]

, 2002
Three isogenic strains of Lactococcus lactis with different levels of H2O-forming NADH oxidase activity were used to study the effect of oxygen on glucose metabolism: the parent strain L.
Vos, W.M., de, Kleerebezem, M., Hugenholtz, J., Ramos, A., Santos, H., Neves, A.R., Costa, H., Swam, I.I., van   +7 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose [PDF]

, 2013
Background Diabetes is a risk factor for respiratory infection, and hyperglycaemia is associated with increased glucose in airway surface liquid and risk of Staphylococcus aureus infection.
Garnett, James P, Tregoning, John S, Baines, DL, Baines, Deborah L, Knight, Gwenan M, Naik, S, Lindsay, JA, Tregoning, JS, Naik, Sonam, Garnett, JP, Baker, EH, Lindsay, Jodi A, Gill, S, Baker, Emma H, Gill, Simren, Knight, GM   +15 more
core   +1 more source

Connexins and Glucose Metabolism in Cancer

International Journal of Molecular Sciences, 2022
Connexins are a family of transmembrane proteins that regulate diverse cellular functions. Originally characterized for their ability to mediate direct intercellular communication through the formation of highly regulated membrane channels, their functions have been extended to the exchange of molecules with the extracellular environment, and the ...
Jones, Jennifer C., Bodenstine, Thomas M.   +1 more
openaire   +2 more sources

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source