Results 161 to 170 of about 491,824 (310)

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Enhanced Detection of Type 2 Diabetes Mellitus in an At-Risk Prediabetic Population Using One-Hour Oral Glucose Tolerance Test (OGTT): A Comparison With HbA1C and Two-Hour OGTT. [PDF]

Cureus
Thenmozhi S, Girija S.
europepmc   +1 more source

Integrated Ultrasound Device for Precision Bladder Volume Monitoring via Acoustic Focusing and Machine Learning

Advanced Science, EarlyView.
We present a conformable wearable ultrasound patch for noninvasive bladder volume monitoring. A flexible PZT array combined with a concave acoustic lens concentrates acoustic energy and improves depth selectivity through the anterior pelvic wall.
Long Long Cao, Feng Wen Wang, Jingwei Xue, Fulei Liu, Ming Liang Jin   +4 more
wiley   +1 more source

Relationship between impaired glucose metabolism and bone mineral density in patients with cystic fibrosis. [PDF]

Eur J Pediatr
Uçar M, Turan H, Kılıç Başkan A, Altun İ, Velioğlu Haşlak G, Karakaş H, Taşkın Z, Bingöl Aydın D, Güney AZ, Beşer ÖF, Kılınç Sakallı AA, Evliyaoğlu O, Bayramoğlu E.   +12 more
europepmc   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

Dependency of Glucose Homeostasis on Pancreatic Enzymes with Special Reference to Amylase; Study on Healthy and Exocrine Pancreatic Insufficient Pigs. [PDF]

Biomolecules
Wychowański P, Pierzynowski SG, Zaworski K, Gallotto R, Szkopek D, Woliński J, Donaldson J, Jacek T, Pierzynowska K.   +8 more
europepmc   +1 more source

Oral glucose tolerance tests.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973
I R, Yudaken, B M, Bloomberg
openaire   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Preclinical pharmacological profiles of cofrogliptin, a novel and bi-weekly DPP-4 inhibitor. [PDF]

Front Pharmacol
Gou X, Dou C, Tang P, Zheng X, Zhang C, Wang J, Meng Q, Wang J.   +7 more
europepmc   +1 more source

Nanozyme Microrobots: Programmable Spatiotemporal Catalysis for Targeted Therapy and Diagnostics

Advanced Science, EarlyView.
This review presents nanozyme microrobots as emerging catalytic systems that integrate mobility, external actuation, and adaptive reactivity to achieve precise biochemical functions. By examining mobility‐regulated catalysis, spatial targeting, integrated designs, and translational demonstrations, the article highlights how nanozyme robotics enables ...
Hong Huy Tran, Nil Kanatha Pandey, David P. Cormode, Daeyeon Lee, Edward Steager, Hyun Koo   +5 more
wiley   +1 more source