Results 181 to 190 of about 491,824 (310)

Evaluation of in vitro and in vivo antidiabetic potential of hydromethanol extract and solvent fraction of the leaves of <i>Ajuga integrifolia</i> (Lamiaceae) in diabetic mice models. [PDF]

Metabol Open
Daba Y, Kitessa M, Ahmed K, Million D, Temesgen A, Amde M, Kiros T, Walo D, Belayneh A, Abdela J.   +9 more
europepmc   +1 more source

Thirty Years of Mentoring by “Bob Chan” of Young Japanese Surgeons to Become Scientists: An Adventure of Love

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Over the past three decades, we have mentored a generation of young Japanese surgeons, guiding them to become internationally recognized surgeon‐scientists. Through a unique collaboration between Japanese academic institutions and our laboratories at AntiCancer Inc.
Robert M. Hoffman, Kentaro Miyake, Itaru Endo   +2 more
wiley   +1 more source

Endocrine Functions of Bone Are Suppressed by Orally Administered Glucose Regardless of Bodyweight. [PDF]

Clin Endocrinol (Oxf)
Jalava N, Heino TJ, Nuutila P, Virtanen KA, Ivaska KK.   +4 more
europepmc   +1 more source

Functional Advantage of Central Pancreatectomy Over Distal Pancreatectomy for Benign or Low‐Grade Malignant Tumors: A Comparative Analysis Based on 75‐g Oral Glucose Tolerance Test

Annals of Gastroenterological Surgery, EarlyView.
Central pancreatectomy (CP) better preserves postoperative pancreatic endocrine function than distal pancreatectomy for benign or low‐grade malignant tumors. The 75‐g oral glucose tolerance test demonstrated that CP maintained insulin secretion and glucose tolerance, highlighting its clinical advantage as a function‐preserving procedure.
Dongha Lee, Keiko Kamei, Chihoko Nobori, Yuta Yoshida, Takaaki Murase, Atsushi Takebe, Yuki Okuda, Naru Babaya, Yoshihisa Hiromine, Ippei Matsumoto   +9 more
wiley   +1 more source

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Role of Medullary AKT and p38 MAPK in Regulating Feeding of Broiler Chicks. [PDF]

J Poult Sci
Saneyasu T, Kaihatsu M, Nagata K, Kitayama A, Sakai H, Kamisoyama H, Takegaki J, Honda K.   +7 more
europepmc   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

Animal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud, Iqbal M. Lone, Kareem Midlej, Fuad A. Iraqi   +3 more
wiley   +1 more source

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source

Effect of Myo-Inositol Treatment on Serum Asprosin Levels of Pregnant Women: A Prospective Randomized Controlled Pilot Study. [PDF]

J Pregnancy
Özay AC, Özay ÖE, Edebal OH, Özay Y, Montanino Oliva M, Dinicola S, Unfer V.   +6 more
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source