Results 171 to 180 of about 8,153 (287)
Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications
Advanced Electronic Materials, EarlyView.This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster +2 more
wiley +1 more source
Coding Synthetic Chemistry Strategies for Furan Valorization into Bacterial Designer Cells**
ChemSusChem, Volume 16, Issue 2, January 20, 2023., 2023 Designer cells: A microbial factory is designed to directly convert furfuryl alcohols to synthetically valuable and enantioenriched delta‐lactones. Pairing Achmatowicz ring expansions and borrowing hydrogen redoxisomerizations, two otherwise non‐natural transformations, this study highlights the potential of introducing novel biocatalytic tools into ...
Yu‐Chang Liu +2 more
wiley +1 more source
Supramolecular Gels as Active Tools for Reaction Engineering
Angewandte Chemie, EarlyView.The unique combination of environments within gels, self‐assembled from low‐molecular‐weight gelators, offers the ability to control reactivity in new ways, achieving unique reaction outcomes, leading to the emerging concept of supramolecular gels as nanoreactors. Smart chemical engineering methods enable the use of such gels to fabricate materials and
David K. Smith
wiley +2 more sources
Development and Application of Organic Sonosensitizers in Cancer Therapy
Aggregate, EarlyView.This review provides a comprehensive overview of organic sonosensitizers employed in cancer treatment, describing their underlying mechanisms and structure‐activity relationship in terms of sonodynamic therapy. The significance of nanotechnology and combination therapy with other oncological modalities (photothermal therapy, photodynamic therapy, etc.)
Yuhan Ding +5 more
wiley +1 more source
Fast and Autonomous Mannosylated Nanomotors for Dynamic Cancer Cell Targeting
Angewandte Chemie, EarlyView.An enzyme‐loaded nanomotor decorated with mannose polymers shows a synergistic effect with respect to cell targeting. The mannose units interact with mannose receptors (MRs) on the cell surface, whereas the presence of the glycopolymer on the motor surface also leads to a more effective motile behavior in cell medium. Abstract An attractive strategy in
Yuechi Liu +12 more
wiley +2 more sources
Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023 Saturated fatty acids induce insulin resistance in neurons. Neuronal metabolism of palmitic acid alters mitochondrial function. Abstract Introduction Saturated fatty acids (FAs) are the main component of high‐fat diets (HFDs), and high consumption has been associated with the development of insulin resistance, endoplasmic reticulum stress and ...
Karina Sánchez‐Alegría +1 more
wiley +1 more source
Electrical Tissue Adhesives for Strain‐Insensitive In‐situ Biosensing
Advanced Intelligent Systems, EarlyView.Interfacing rigid, non‐stretchable biosensors with soft, deformable tissues presents significant challenges due to their fundamentally contradictory properties. This work reports an electrical tissue adhesive featuring an entangled adhesive polymer network interpenetrated with a sacrificial dissipative polymer network that can rapidly and robustly ...
Tsz Hung Wong +10 more
wiley +1 more source
Evaluation of Trinder's Glucose Oxidase Method for Measuring Glucose in Serum and Urine
, 1975 John A. Lott, Kathie Turner
openalex +1 more source
Purine Metabolism and Dystonia: Perspectives of a Long‐Promised Relationship
Annals of Neurology, EarlyView.Purine pool imbalance in purine metabolism disorders, such as Lesch–Nyhan disease, intersects with dystonia pathogenesis. The recent discovery of gain‐of‐function IMPDH2 pathogenic variants in patients with prominent dystonic manifestations provides new insights into the link between dystonia and purinergic system defects.
Ugo Sorrentino +4 more
wiley +1 more source
The thioredoxin system: Balancing redox responses in immune cells and tumors
European Journal of Immunology, Volume 53, Issue 1, January 2023., 2023 The thioredoxin (TRX) system is a critical contributor to cellular redox homeostasis in all living cells. Here, we review the key roles of TRX for activation, proliferation, and responses in T cells, B cells, and myeloid cells. Further, we conceptualize how this knowledge may be therapeutically exploited for cancer treatment.
Jonathan Muri, Manfred Kopf
wiley +1 more source