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Facilitative glucose transporters [PDF]
European Journal of Biochemistry, 1994 Facilitative glucose transport is mediated by members of the Glut protein family that belong to a much larger superfamily of 12 transmembrane segment transporters. Six members of the Glut family have been described thus far. These proteins are expressed in a tissue‐ and cell‐specific manner and exhibit distinct kinetic and regulatory properties that ...
Mike Mueckler
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The GLUT4 glucose transporter. [PDF]
Cell Metabolism, 2007 Few physiological parameters are more tightly and acutely regulated in humans than blood glucose concentration. The major cellular mechanism that diminishes blood glucose when carbohydrates are ingested is insulin-stimulated glucose transport into skeletal muscle.
Shaohui Huang, M. Czech
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Structure and mechanism of a phosphotransferase system glucose transporter [PDF]
Nature CommunicationsGlucose is the primary source of energy for many organisms and is efficiently taken up by bacteria through a dedicated transport system that exhibits high specificity.
Patrick Roth +5 more
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Osteopontin upregulates the expression of glucose transporters in osteosarcoma cells. [PDF]
PLoS ONE, 2014 Osteosarcoma is the most common primary malignancy of bone. Even after the traditional standard surgical therapy, metastasis still occurs in a high percentage of patients.
I-Shan Hsieh, Rong-Sen Yang, Wen-Mei Fu
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Glucose Transport and Transporters in the Endomembranes [PDF]
International Journal of Molecular Sciences, 2019 Glucose is a basic nutrient in most of the creatures; its transport through biological membranes is an absolute requirement of life. This role is fulfilled by glucose transporters, mediating the transport of glucose by facilitated diffusion or by secondary active transport.
Beáta Lizák +8 more
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Current understanding of glucose transporter 4 expression and functional mechanisms
World Journal of Biological Chemsitry, 2020 Glucose is used aerobically and anaerobically to generate energy for cells. Glucose transporters (GLUTs) are transmembrane proteins that transport glucose across the cell membrane.
Tiannan Wang +4 more
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Assessing glucose uptake through the yeast hexose transporter 1 (Hxt1). [PDF]
PLoS ONE, 2015 The transport of glucose across the plasma membrane is mediated by members of the glucose transporter family. In this study, we investigated glucose uptake through the yeast hexose transporter 1 (Hxt1) by measuring incorporation of 2-NBDG, a non ...
Adhiraj Roy +3 more
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Glucose Metabolism and Glucose Transporters in Breast Cancer [PDF]
Frontiers in Cell and Developmental Biology, 2021 Breast cancer is the most common malignancy in women worldwide and is associated with high mortality rates despite the continuously advancing treatment strategies. Glucose is essential for cancer cell metabolism owing to the Warburg effect. During the process of glucose metabolism, various glycolytic metabolites, such as serine and glycine metabolites,
Ja Seung Koo, Eunah Shin
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Dysregulation of Glucose Homeostasis Following Chronic Exogenous Administration of Leptin in Healthy Sprague-Dawley Rats [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: Impaired glucose utilization is seen in chronic hyperleptinaemia associated conditions such as obesity and type 2 diabetes mellitus. It is unclear if this impaired glucose utilization is due to the effect of persistent hyperleptinaemia on
Khalil Wjidan +4 more
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Human Glucose Transporters in Renal Glucose Homeostasis [PDF]
International Journal of Molecular Sciences, 2021 The kidney plays an important role in glucose homeostasis by releasing glucose into the blood stream to prevent hypoglycemia. It is also responsible for the filtration and subsequent reabsorption or excretion of glucose. As glucose is hydrophilic and soluble in water, it is unable to pass through the lipid bilayer on its own; therefore, transport takes
Aleksandra Sędzikowska +1 more
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