Structure and mechanism of a phosphotransferase system glucose transporter [PDF]
Nature CommunicationsGlucose is the primary source of energy for many organisms and is efficiently taken up by bacteria through a dedicated transport system that exhibits high specificity.
Patrick Roth +5 more
doaj +2 more sources
Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]
, 2012 Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
A Adaikalakoteswari +42 more
core +12 more sources
Osteopontin upregulates the expression of glucose transporters in osteosarcoma cells. [PDF]
PLoS ONE, 2014 Osteosarcoma is the most common primary malignancy of bone. Even after the traditional standard surgical therapy, metastasis still occurs in a high percentage of patients.
I-Shan Hsieh, Rong-Sen Yang, Wen-Mei Fu
doaj +1 more source
Kinetoplastid glucose transporters [PDF]
Biochemical Journal, 1997 Protozoa of the order kinetoplastida have colonized many habitats, and several species are important parasites of humans. Adaptation to different environments requires an associated adaptation at a cell's interface with its environment, i.e. the plasma membrane.
E, Tetaud +3 more
openaire +2 more sources
Assessing glucose uptake through the yeast hexose transporter 1 (Hxt1). [PDF]
PLoS ONE, 2015 The transport of glucose across the plasma membrane is mediated by members of the glucose transporter family. In this study, we investigated glucose uptake through the yeast hexose transporter 1 (Hxt1) by measuring incorporation of 2-NBDG, a non ...
Adhiraj Roy +3 more
doaj +1 more source
Programming Skeletal Muscle Metabolic Flexibility in Offspring of Male Rats in Response to Maternal Consumption of Slow Digesting Carbohydrates during Pregnancy [PDF]
, 2020 Skeletal muscle plays a relevant role in metabolic flexibility and fuel usage and the associated muscle metabolic inflexibility due to high-fat diets contributing to obesity and type 2 diabetes.
Andújar, Eloísa +7 more
core +1 more source
Dysregulation of Glucose Homeostasis Following Chronic Exogenous Administration of Leptin in Healthy Sprague-Dawley Rats [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: Impaired glucose utilization is seen in chronic hyperleptinaemia associated conditions such as obesity and type 2 diabetes mellitus. It is unclear if this impaired glucose utilization is due to the effect of persistent hyperleptinaemia on
Khalil Wjidan +4 more
doaj +1 more source
GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker
Clinics, 2011 OBJECTIVE: To analyze glucose transporter 1 expression patterns in malignant tumors of various cell types and evaluate their diagnostic value by immunohistochemistry.
Kátia C. Carvalho +9 more
doaj +1 more source
Tacrolimus Induces Insulin Resistance and Increases the Glucose Absorption in the Jejunum: A Potential Mechanism of the Diabetogenic Effects. [PDF]
PLoS ONE, 2015 The use of the immunosuppressive drug tacrolimus (TAC) is related to new onset diabetes after transplantation. Herein, we examined the effect of intraperitoneal administered TAC on intestinal glucose absorption in mice.Animals received low, medium, or ...
Zhiwei Li +9 more
doaj +1 more source
Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality [PDF]
, 2010 A Plasmodium falciparum hexose transporter (PfHT) has previously been shown to be a facilitative glucose and fructose transporter. Its expression in Xenopus laevis oocytes and the use of a glucose analogue inhibitor permitted chemical validation of PfHT ...
Doerig, C +6 more
core +2 more sources