Results 101 to 110 of about 1,374,974 (361)

Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats. [PDF]

, 1989
Barbara B. Kahn, Maureen Charron, Harvey F. Lodish, Samuel W. Cushman, Jeffrey S. Flier   +4 more
openalex   +1 more source

Hydroxychloroquine Associated with Lower Glomerular Filtration Rate Decline in Lupus Nephritis

Arthritis Care &Research, Accepted Article.
Background Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical. Therefore, we analyzed data from our
Shivani Garg, Brad Rovin, Brad C. Astor, Tripti Singh, Fauzia Hollnagel, Megan Kuik, Lexie Kolton, Callie Saric, S. Sam Lim, Christie M. Bartels   +9 more
wiley   +1 more source

Physiological functions of glucose transporter-2: From cell physiology to links with diabetes mellitus

Heliyon
Glucose is a sugar crucial for human health since it participates in many biochemical reactions. It produces adenosine 5′-triphosphate (ATP) and nucleosides through glucose metabolic and pentose phosphate pathways.
Zhean Shen, Yingze Hou, Guo Zhao, Libi Tan, Jili Chen, Ziqi Dong, Chunxiao Ni, Longying Pei   +7 more
doaj  

Mechanisms of Cardiovascular Benefits of Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors

JACC: Basic to Translational Science, 2020
G. Lopaschuk, S. Verma
semanticscholar   +1 more source

A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo

Molecular Cancer Therapeutics, 2012
The functional and therapeutic importance of the Warburg effect is increasingly recognized, and glycolysis has become a target of anticancer strategies.
Yi Liu, Yanyan Cao, Weihe Zhang, S. Bergmeier, Yanrong Qian, H. Akbar, R. Colvin, Juan Ding, Lingying Tong, Shiyong Wu, J. Hines, Xiaozhuo Chen   +11 more
semanticscholar   +1 more source

Structural basis of human erythrocyte glucose transporter function in proteoliposome vesicles: circular dichroism measurements. [PDF]

, 1987
Jeffery Chin, E K Jung, V Chen, Chan Y. Jung   +3 more
openalex   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

The di-peptide Trp-His activates AMP-activated protein kinase and enhances glucose uptake independently of insulin in L6 myotubes

FEBS Open Bio, 2014
The di-peptide Trp-His (WH) has vasorelaxant and anti-atherosclerotic functions. We hypothesized that WH has multiple biological functions and may aid AMP-activated protein kinase (AMPK) activation and affect the glucose transport system in skeletal ...
Minoru Soga, Ayaka Ohashi, Megumi Taniguchi, Toshiro Matsui, Takanori Tsuda   +4 more
doaj   +1 more source

Expression of a Glucose Transporter Gene Cloned from Brain in Cellular Models of Insulin Resistance: Dexamethasone Decreases Transporter mRNA in Primary Cultured Adipocytes [PDF]

, 1989
W. Timothy Garvey, Thomas P. Huecksteadt, Fábio Bessa Lima, Morris J. Birnbaum   +3 more
openalex   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source