Results 131 to 140 of about 1,374,974 (361)

Genetically engineered insulin mediated by glucose transporter-2 (GLUT2) promoter for the biosynthesis of insulin in rat hepatocytes

open access: yesJournal of BioScience and Biotechnology
The expression of insulin in hepatocytes by hepatic gene therapy is a promising treatment for diabetes. The conversion of immature proinsulin to mature insulin occurs only in cells that contain the enzymes responsible for the ...
Gehad Elsayed Mahmoud
doaj  

Unassisted Photoelectrochemical Hydrogen Production Coupled with Selective Glucose Oxidation Using Metal Halide Perovskite Photoanodes

open access: yesAdvanced Functional Materials, EarlyView.
A metal halide perovskite‐based photoanode integrated with a CoNiFe layered double hydroxide (LDH) cocatalyst is reported for selective glucose oxidation reaction (GOR), achieving simultaneous and unassisted photoelectrochemical hydrogen production. This system delivers high photocurrent density, excellent Faradaic efficiency of GOR, and strong techno ...
Shujie Zhou   +12 more
wiley   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

open access: yesAdvanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen   +9 more
wiley   +1 more source

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

open access: yesAdvanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar   +6 more
wiley   +1 more source

A Universal Way to Manipulate Droplet via Light‐Fueled Thermocapillary Convection

open access: yesAdvanced Functional Materials, EarlyView.
A non‐contact light‐induced droplet manipulation strategy fueled by mid‐infrared (MIR) light irradiation is introduced. No additional additives and/or complex substrate are required. Here, thermocapillary convection, directly generated by temperature gradient at outer surface of droplet via localized surface heating, plays a key role to propel the ...
Hyesun Hwang   +5 more
wiley   +1 more source

Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2016
K. Kapoor   +10 more
semanticscholar   +1 more source

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

open access: yesAdvanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung   +6 more
wiley   +1 more source

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