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Glucose Transporters in the Thyroid
Thyroid, 2005Glucose transport, mediated by proteins expressed from the glucose transporter genes, plays an essential role in cellular metabolism. Increased uptake of glucose compared to cells in normal tissue is a defining characteristic of malignant cells.
Orlo H. Clark +5 more
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Trypanosome glucose transporters
Molecular and Biochemical Parasitology, 1998, by contrast adopts an intracellularenvironment within their mammalian hosts. Inva-sion and passage through different anatomicallocations within insect vectors also distinguishesthe parasites.All trypanosome species use glucose as a crucialsource of energy, and all have specific plasmamembrane transporters to facilitate the uptake ofthis molecule. Four
Théo Baltz +4 more
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Regulated transport of the glucose transporter GLUT4
Nature Reviews Molecular Cell Biology, 2002In muscle and fat cells, insulin stimulates the delivery of the glucose transporter GLUT4 from an intracellular location to the cell surface, where it facilitates the reduction of plasma glucose levels. Understanding the molecular mechanisms that mediate this translocation event involves integrating our knowledge of two fundamental processes--the ...
Bryant, Nia J +2 more
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Glucose transport in the heart
Frontiers in Bioscience, 2004The heart is a unique organ in many ways. It consists of specialized muscle cells (cardiomyocytes), which are adapted to contract constantly in a coordinated fashion. This is vital to the survival of the organism given the central role of the heart in the maintenance of the cardiovascular system that delivers oxygen, metabolic substrates and hormones ...
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Advances in Pediatrics, 1998
Concentrative and facilitative glucose transporters are responsible for the movement of glucose across the plasma membrane of human cells. Defects in concentrative glucose transporters cause renal glycosuria and glucose-galactose malabsorption. Alterations in facilitative glucose transporters explain the newly discovered syndrome of low CNS glucose in ...
N, Longo, L J, Elsas
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Concentrative and facilitative glucose transporters are responsible for the movement of glucose across the plasma membrane of human cells. Defects in concentrative glucose transporters cause renal glycosuria and glucose-galactose malabsorption. Alterations in facilitative glucose transporters explain the newly discovered syndrome of low CNS glucose in ...
N, Longo, L J, Elsas
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The dynamics of the glucose transporter
Trends in Biochemical Sciences, 1988Abstract Recent advances in characterizing the molecular structure and kinetic properties of the human erythrocyte glucose transporter are now starting to give an insight into the dynamics of the transporter.
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Diabetes Care, 1992
Three major metabolic abnormalities contribute to hyperglycemia in non-insulin-dependent diabetes mellitus (NIDDM) including defective glucose-induced insulin secretion, elevated rates of hepatic glucose output, and insulin's impaired ability to stimulate glucose uptake in peripheral target tissues (insulin resistance). These functions involve cellular
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Three major metabolic abnormalities contribute to hyperglycemia in non-insulin-dependent diabetes mellitus (NIDDM) including defective glucose-induced insulin secretion, elevated rates of hepatic glucose output, and insulin's impaired ability to stimulate glucose uptake in peripheral target tissues (insulin resistance). These functions involve cellular
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TISSUE GLUCOSE TRANSPORT AND GLUCOSE TRANSPORTERS IN SUCKLING RATS WITH ENDOTOXIC SHOCK
Shock, 1996Hypoglycemia occurs without hyperinsulinemia in suckling rats with endotoxic shock. However, tissue glucose uptake during endotoxic shock is not well known in the newborn. GLUT1 is insulin insensitive and is the predominant glucose transporter in 10 day old rats.
Ciril Krzisnik +3 more
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Exercise training, glucose transporters, and glucose transport in rat skeletal muscles
American Journal of Physiology-Cell Physiology, 1992It was previously found that voluntary wheel running induces an increase in the insulin-sensitive glucose transporter, i.e., the GLUT4 isoform, in rat plantaris muscle (K. J. Rodnick, J. O. Holloszy, C. E. Mondon, and D. E. James. Diabetes 39: 1425-1429, 1990).
Kenneth J. Rodnick +3 more
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1990
The human erythrocyte glucose transporter is a fully integrated membrane glycoprotein having only one N-linked carbohydrate chain on the extracellular part of the molecule. Several authors have suggested the involvement of the carbohydrate moiety in glucose transport, but not definitive results have been published to date. Using transport glycoproteins
Yves Goussault +5 more
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The human erythrocyte glucose transporter is a fully integrated membrane glycoprotein having only one N-linked carbohydrate chain on the extracellular part of the molecule. Several authors have suggested the involvement of the carbohydrate moiety in glucose transport, but not definitive results have been published to date. Using transport glycoproteins
Yves Goussault +5 more
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