Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao+12 more
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Effects of Sintilimab Plus Radiotherapy on Levels of Spondin-2 and Glucose Transporter-1 in Patients with Cervical Cancer. [PDF]
Yang H, Chen Z, Lou H, Ying W, Chai Z.
europepmc +1 more source
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao+14 more
wiley +1 more source
Upregulated expression of glucose transporter isoform 1 in invasive and metastatic extramammary Paget's disease. [PDF]
Matsumoto M+7 more
europepmc +1 more source
Upregulation of Transferrin Receptor 1 (TfR1) but Not Glucose Transporter 1 (GLUT1) or CD98hc at the Blood-Brain Barrier in Response to Valproic Acid. [PDF]
Helgudóttir SS+5 more
europepmc +1 more source
Mast Cells are Dependent on Glucose Transporter 1 (GLUT1) and GLUT3 for IgE-mediated Activation. [PDF]
Grujic M+4 more
europepmc +1 more source
Glucose transporter-1 deficiency syndrome with extreme phenotypic variability in a five-generation family carrying a novel SLC2A1 variant. [PDF]
Giugno A+9 more
europepmc +1 more source
Expanding therapeutic horizons: glucagon-like peptide-1 receptor agonists and sodium glucose transporter-2 inhibitors in poly cystic ovarian syndrome: a comprehensive review including systematic review and network meta-analysis of randomized clinical trials. [PDF]
Sridharan K, Sivaramakrishnan G.
europepmc +1 more source
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Glucose transport in lymphocytes
Pflügers Archiv - European Journal of Physiology, 2020Glucose uptake into lymphocytes is accomplished by non-concentrative glucose carriers of the GLUT family (GLUT1, GLUT3, GLUT4, GLUT6) and/or by the Na+-coupled glucose carrier SGLT1. The latter accumulates glucose against glucose gradients and is still effective at very low extracellular glucose concentrations.
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openaire +2 more sources
The recent cloning of families of glucose transporters has made it possible to study their structure and their role in an increasing number of disease states. Two classes of glucose transporters transfer glucose across the plasma membrane of human cells.
L J, Elsas, N, Longo
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