Results 341 to 350 of about 408,864 (383)
Some of the next articles are maybe not open access.
Diabetes Care, 1992
Three major metabolic abnormalities contribute to hyperglycemia in non-insulin-dependent diabetes mellitus (NIDDM) including defective glucose-induced insulin secretion, elevated rates of hepatic glucose output, and insulin's impaired ability to stimulate glucose uptake in peripheral target tissues (insulin resistance). These functions involve cellular
openaire +3 more sources
Three major metabolic abnormalities contribute to hyperglycemia in non-insulin-dependent diabetes mellitus (NIDDM) including defective glucose-induced insulin secretion, elevated rates of hepatic glucose output, and insulin's impaired ability to stimulate glucose uptake in peripheral target tissues (insulin resistance). These functions involve cellular
openaire +3 more sources
TISSUE GLUCOSE TRANSPORT AND GLUCOSE TRANSPORTERS IN SUCKLING RATS WITH ENDOTOXIC SHOCK
Shock, 1996Hypoglycemia occurs without hyperinsulinemia in suckling rats with endotoxic shock. However, tissue glucose uptake during endotoxic shock is not well known in the newborn. GLUT1 is insulin insensitive and is the predominant glucose transporter in 10 day old rats.
Ciril Krzisnik +3 more
openaire +3 more sources
Exercise training, glucose transporters, and glucose transport in rat skeletal muscles
American Journal of Physiology-Cell Physiology, 1992It was previously found that voluntary wheel running induces an increase in the insulin-sensitive glucose transporter, i.e., the GLUT4 isoform, in rat plantaris muscle (K. J. Rodnick, J. O. Holloszy, C. E. Mondon, and D. E. James. Diabetes 39: 1425-1429, 1990).
Kenneth J. Rodnick +3 more
openaire +3 more sources
Facilitative glucose transport proteins and sodium-glucose co-transporters in the kidney
Current Opinion in Nephrology and Hypertension, 1995Cloning studies have characterized a large gene family of facilitative glucose transporters that are expressed in a tissue-specific manner, and at least two sodium-glucose co-transporters in brush-border membranes of intestinal and renal epithelia. These different transporters play specific roles in glucose transport and homeostasis because of their ...
Brenda B. Hoffman, Fuad N. Ziyadeh
openaire +3 more sources
1993
Decreased peripheral utilization of glucose is an important pathogenic mechanism in diabetes. Although it is universally acknowledged that insulin resistance plays a major role in the reduction of glucose consumption by peripheral tissues, and many defects have been described in the function of insulin receptors (see chapter by Olefsky), indirect ...
Danielle Melloul +3 more
openaire +3 more sources
Decreased peripheral utilization of glucose is an important pathogenic mechanism in diabetes. Although it is universally acknowledged that insulin resistance plays a major role in the reduction of glucose consumption by peripheral tissues, and many defects have been described in the function of insulin receptors (see chapter by Olefsky), indirect ...
Danielle Melloul +3 more
openaire +3 more sources
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1990
The human erythrocyte glucose transporter is a fully integrated membrane glycoprotein having only one N-linked carbohydrate chain on the extracellular part of the molecule. Several authors have suggested the involvement of the carbohydrate moiety in glucose transport, but not definitive results have been published to date. Using transport glycoproteins
Yves Goussault +5 more
openaire +3 more sources
The human erythrocyte glucose transporter is a fully integrated membrane glycoprotein having only one N-linked carbohydrate chain on the extracellular part of the molecule. Several authors have suggested the involvement of the carbohydrate moiety in glucose transport, but not definitive results have been published to date. Using transport glycoproteins
Yves Goussault +5 more
openaire +3 more sources
Glucose transport in the equine hoof
Equine Veterinary Journal, 2011Several conditions associated with laminitis in horses are also associated with insulin resistance, which represents the failure of glucose uptake via the insulin-responsive glucose transport proteins in certain tissues. Glucose starvation is a possible mechanism of laminitis, but glucose uptake mechanisms in the hoof are not well understood.To ...
Asplin, Katie +4 more
openaire +4 more sources
Glucose Transport in Lactation
2004Lactose is the major carbohydrate of human milk and is also the major osmotic constituent of human milk. Therefore, synthesis of lactose is the major determinant of the volume of milk produced by the lactating human mammary gland. Lactose issynthesized from free glucose and UDP-galactose.
openaire +3 more sources
Diabetes, 1992
To investigate the role of glucose in regulating glucose transporters in pancreatic β-cells, we studied the hamster clonal β-cell line HIT-T15, which retains responsiveness to glucose. Northern blot analysis demonstrates that GLUT2 and GLUT1 mRNA are abundant in HIT cells. After a 24-h culture with various concentrations of glucose (0–22.2 mM [0–400 mg/
Kenichi Imagawa +10 more
openaire +3 more sources
To investigate the role of glucose in regulating glucose transporters in pancreatic β-cells, we studied the hamster clonal β-cell line HIT-T15, which retains responsiveness to glucose. Northern blot analysis demonstrates that GLUT2 and GLUT1 mRNA are abundant in HIT cells. After a 24-h culture with various concentrations of glucose (0–22.2 mM [0–400 mg/
Kenichi Imagawa +10 more
openaire +3 more sources
The Glucose Transporter of Mammalian Cells
Annual Review of Physiology, 1982The glucose transporter is now identified but may have modifications or other subunits that control its activity. The kinetics and inhibitor binding studies are consistent with the carrier model with different degrees of asymmetry and a single binding site that varies in specificity depending on the conformation of the protein.
Peter C. Hinkle, Thomas J. Wheeler
openaire +3 more sources