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Glucose transporters in preimplantation development
Reviews of Reproduction, 1998The inability of the embryo to utilize glucose as a fuel before compaction has been an area of much speculation. It is suggested that limitations in glucose transporter processes are the prime reasons for this. The recent identification of GLUT3 as the transporter responsible for the uptake of maternal glucose after compaction may provide the missing ...
Pantaleon M., Kaye P.L.
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Glucose transport in liposomes [PDF]
Biochemistry and Molecular Biology Education, 2003 AbstractTerms to be familiar with before you start to solve the test: lipoprotein membranes, liposomes, Na+,K+‐ATPase, Na+/glucose symporter, glucose transporter.
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Glucose transporters and diabetes
Seminars in Cell & Developmental Biology, 1996Abstract Peripheral insulin resistance is a characteristic feature of obesity and non-insulin-dependent diabetes mellitus (NIDDM), and the cause can be localized in part to a defect in glucose transport. GLUT4, the predominant glucose transporter in insulin sensitive tissues, undergoes striking tissue specific metabolic regulation; GLUT4 gene ...
Karen L. Houseknecht +2 more
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Glucose transport and apoptosis.
Apoptosis : an international journal on programmed cell death, 2000The transport and metabolism of glucose modify programmed cell death in a number of different cell types. This review presents three cell death paradigms that link a decrease in glucose transport to apoptosis. Although these pathways overlap, the glucose-dependent stimuli that trigger cell death differ.
M M Mueckler, K H Moley
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Glucose, glucose transporters and neurogenesis
2008Since the pioneering work of Altman in the late 60's, much has been learned about the generation of neurons in the adult brains of several species, including mice, rats, and humans. An underlying assumption is that these newborn neurons acquire their energy, in the form of glucose, in a similar manner to mature neurons: via glucose transporters.
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Expression of glucose transporters in cancers
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2013It has been known for 80 years that cancer cell growth in an energy-related process supported by an increased glucose metabolism. This phenomenon suggests a need for a corresponding increased uptake of glucose across the plasma membrane through an enhancement in the glucose transporter proteins, SGLT proteins as well as GLUT proteins.
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Cellular Regulation of Glucose Uptake by Glucose Transporter GLUT4
2014GLUT4 is regulated by its intracellular localization. In the absence of insulin, GLUT4 is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation (and contraction in muscle), GLUT4 translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu
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