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Glucose transport in the equine hoof
Equine Veterinary Journal, 2011Several conditions associated with laminitis in horses are also associated with insulin resistance, which represents the failure of glucose uptake via the insulin-responsive glucose transport proteins in certain tissues. Glucose starvation is a possible mechanism of laminitis, but glucose uptake mechanisms in the hoof are not well understood.To ...
Asplin, Katie +4 more
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Endocrinology, 1990
Two cell lines have been established from insulinomas obtained by targeted expression of the simian virus 40 T antigen gene in transgenic mice.
J. Miyazaki +7 more
semanticscholar +1 more source
Two cell lines have been established from insulinomas obtained by targeted expression of the simian virus 40 T antigen gene in transgenic mice.
J. Miyazaki +7 more
semanticscholar +1 more source
Diabetes, 1992
To investigate the role of glucose in regulating glucose transporters in pancreatic β-cells, we studied the hamster clonal β-cell line HIT-T15, which retains responsiveness to glucose. Northern blot analysis demonstrates that GLUT2 and GLUT1 mRNA are abundant in HIT cells. After a 24-h culture with various concentrations of glucose (0–22.2 mM [0–400 mg/
Kenichi Imagawa +10 more
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To investigate the role of glucose in regulating glucose transporters in pancreatic β-cells, we studied the hamster clonal β-cell line HIT-T15, which retains responsiveness to glucose. Northern blot analysis demonstrates that GLUT2 and GLUT1 mRNA are abundant in HIT cells. After a 24-h culture with various concentrations of glucose (0–22.2 mM [0–400 mg/
Kenichi Imagawa +10 more
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The Glucose Transporter of Mammalian Cells
Annual Review of Physiology, 1982The glucose transporter is now identified but may have modifications or other subunits that control its activity. The kinetics and inhibitor binding studies are consistent with the carrier model with different degrees of asymmetry and a single binding site that varies in specificity depending on the conformation of the protein.
Peter C. Hinkle, Thomas J. Wheeler
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Glucose transporters in preimplantation development
Reviews of Reproduction, 1998The inability of the embryo to utilize glucose as a fuel before compaction has been an area of much speculation. It is suggested that limitations in glucose transporter processes are the prime reasons for this. The recent identification of GLUT3 as the transporter responsible for the uptake of maternal glucose after compaction may provide the missing ...
Pantaleon M., Kaye P.L.
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Glucose transport in liposomes [PDF]
Biochemistry and Molecular Biology Education, 2003 AbstractTerms to be familiar with before you start to solve the test: lipoprotein membranes, liposomes, Na+,K+‐ATPase, Na+/glucose symporter, glucose transporter.
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Glucose transporters and diabetes
Seminars in Cell & Developmental Biology, 1996Abstract Peripheral insulin resistance is a characteristic feature of obesity and non-insulin-dependent diabetes mellitus (NIDDM), and the cause can be localized in part to a defect in glucose transport. GLUT4, the predominant glucose transporter in insulin sensitive tissues, undergoes striking tissue specific metabolic regulation; GLUT4 gene ...
Karen L. Houseknecht +2 more
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Glucose, glucose transporters and neurogenesis
2008Since the pioneering work of Altman in the late 60's, much has been learned about the generation of neurons in the adult brains of several species, including mice, rats, and humans. An underlying assumption is that these newborn neurons acquire their energy, in the form of glucose, in a similar manner to mature neurons: via glucose transporters.
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Expression of glucose transporters in cancers
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2013It has been known for 80 years that cancer cell growth in an energy-related process supported by an increased glucose metabolism. This phenomenon suggests a need for a corresponding increased uptake of glucose across the plasma membrane through an enhancement in the glucose transporter proteins, SGLT proteins as well as GLUT proteins.
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