Results 41 to 50 of about 408,864 (383)
Effects of insulin on glucose transport and glucose transporters in rat heart [PDF]
The effect of insulin on glucose transport and glucose transporters was studied in perfused rat heart. Glucose transport was measured by the efflux of labelled 3-O-methylglucose from hearts preloaded with this hexose. Insulin stimulated 3-O-methylglucose transport by: (a) doubling the maximal velocity (Vmax); (b) decreasing the Kd from 6.9 to 2.7 mM ...
Bernard Jeanrenaud+3 more
openaire +3 more sources
Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE. [PDF]
The major facilitator superfamily (MFS) is the largest collection of structurally related membrane proteins that transport a wide array of substrates.
Gonen, Tamir+4 more
core +3 more sources
Introduction Sodium glucose co‐transporter 2 inhibitors constitute a new class of antidiabetic medication. Sodium glucose co‐transporter 2 inhibitors have been shown to exert anticancer effects.
Keita Izumi+4 more
doaj +1 more source
The first and limiting step of metabolism of glucose, the most widespread carbon and energy source for majority of cells, is the transport of this sugar across cytoplasmic membrane.
O. G. Stasyk+3 more
doaj +1 more source
The glucose sensor-like protein Hxs1 is a high-affinity glucose transporter and required for virulence in Cryptococcus neoformans. [PDF]
Cryptococcus is a major fungal pathogen that frequently causes systemic infection in patients with compromised immunity. Glucose, an important signal molecule and the preferred carbon source for Cryptococcus, plays a critical role in fungal development ...
Tong-Bao Liu+5 more
doaj +1 more source
A novel delta current method for transport stoichiometry estimation. [PDF]
BackgroundThe ion transport stoichiometry (q) of electrogenic transporters is an important determinant of their function. q can be determined by the reversal potential (Erev) if the transporter under study is the only electrogenic transport mechanism or ...
Kao, Liyo, Kurtz, Ira, Shao, Xuesi M
core +1 more source
More on glucose transporters: The acinar organization for hepatic glucose transport [PDF]
The “erythroid/brain” glucose transporter (GT) isoform is expressed only in a subset of hepatocytes, those forming the first row around the terminal hepatic venules, while the “liver” GT is expressed in all hepatocytes. After 3 d of starvation, a three- to fourfold elevation of expression of the erythroid/brain GT mRNA and ...
Jorge J. Gumucio+2 more
openaire +4 more sources
The antipsychotic drug olanzapine is widely prescribed to treat schizophrenia and other psychotic disorders. However, it often causes unwanted side effects, including diabetes, due to disruption of insulin‐dependant glucose metabolism through a mechanism
Petr Babkin+4 more
doaj +1 more source
An evolved xylose transporter from
Background Xylose is a second most abundant sugar component of lignocellulose besides glucose. Efficient fermentation of xylose is important for the economics of biomass-based biorefineries.
Zhang Jingqing+4 more
doaj +1 more source
GLUT1 expression patterns in different Hodgkin lymphoma subtypes and progressively transformed germinal centers [PDF]
Background: Increased glycolytic activity is a hallmark of cancer, allowing staging and restaging with 18F-fluorodeoxyglucose-positron-emission-tomography (PET).
Agostinelli, Claudio+9 more
core +1 more source