Results 41 to 50 of about 408,864 (383)

Effects of insulin on glucose transport and glucose transporters in rat heart [PDF]

open access: yesBiochemical Journal, 1988
The effect of insulin on glucose transport and glucose transporters was studied in perfused rat heart. Glucose transport was measured by the efflux of labelled 3-O-methylglucose from hearts preloaded with this hexose. Insulin stimulated 3-O-methylglucose transport by: (a) doubling the maximal velocity (Vmax); (b) decreasing the Kd from 6.9 to 2.7 mM ...
Bernard Jeanrenaud   +3 more
openaire   +3 more sources

Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE. [PDF]

open access: yes, 2014
The major facilitator superfamily (MFS) is the largest collection of structurally related membrane proteins that transport a wide array of substrates.
Gonen, Tamir   +4 more
core   +3 more sources

Clinical response to sodium glucose co‐transporter 2 inhibitor ipragliflozin in a patient with metastatic renal cell carcinoma

open access: yesIJU Case Reports, 2019
Introduction Sodium glucose co‐transporter 2 inhibitors constitute a new class of antidiabetic medication. Sodium glucose co‐transporter 2 inhibitors have been shown to exert anticancer effects.
Keita Izumi   +4 more
doaj   +1 more source

Expression of genes of putative hexose transporters in the yeast Hansenula polymorpha are differentially regulated by glucose sensors Hxs1 and Gcr1

open access: yesБіологічні студії, 2012
The first and limiting step of metabolism of glucose, the most widespread carbon and energy source for majority of cells, is the transport of this sugar across cytoplasmic membrane.
O. G. Stasyk   +3 more
doaj   +1 more source

The glucose sensor-like protein Hxs1 is a high-affinity glucose transporter and required for virulence in Cryptococcus neoformans. [PDF]

open access: yesPLoS ONE, 2013
Cryptococcus is a major fungal pathogen that frequently causes systemic infection in patients with compromised immunity. Glucose, an important signal molecule and the preferred carbon source for Cryptococcus, plays a critical role in fungal development ...
Tong-Bao Liu   +5 more
doaj   +1 more source

A novel delta current method for transport stoichiometry estimation. [PDF]

open access: yes, 2014
BackgroundThe ion transport stoichiometry (q) of electrogenic transporters is an important determinant of their function. q can be determined by the reversal potential (Erev) if the transporter under study is the only electrogenic transport mechanism or ...
Kao, Liyo, Kurtz, Ira, Shao, Xuesi M
core   +1 more source

More on glucose transporters: The acinar organization for hepatic glucose transport [PDF]

open access: yesHepatology, 1991
The “erythroid/brain” glucose transporter (GT) isoform is expressed only in a subset of hepatocytes, those forming the first row around the terminal hepatic venules, while the “liver” GT is expressed in all hepatocytes. After 3 d of starvation, a three- to fourfold elevation of expression of the erythroid/brain GT mRNA and ...
Jorge J. Gumucio   +2 more
openaire   +4 more sources

Antipsychotics inhibit glucose transport: Determination of olanzapine binding site inStaphylococcus epidermidis glucose/H+ symporter

open access: yesFEBS Open Bio, 2015
The antipsychotic drug olanzapine is widely prescribed to treat schizophrenia and other psychotic disorders. However, it often causes unwanted side effects, including diabetes, due to disruption of insulin‐dependant glucose metabolism through a mechanism
Petr Babkin   +4 more
doaj   +1 more source

An evolved xylose transporter from Zymomonas mobilis enhances sugar transport in Escherichia coli

open access: yesMicrobial Cell Factories, 2009
Background Xylose is a second most abundant sugar component of lignocellulose besides glucose. Efficient fermentation of xylose is important for the economics of biomass-based biorefineries.
Zhang Jingqing   +4 more
doaj   +1 more source

GLUT1 expression patterns in different Hodgkin lymphoma subtypes and progressively transformed germinal centers [PDF]

open access: yes, 2012
Background: Increased glycolytic activity is a hallmark of cancer, allowing staging and restaging with 18F-fluorodeoxyglucose-positron-emission-tomography (PET).
Agostinelli, Claudio   +9 more
core   +1 more source

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