Results 31 to 40 of about 11,448 (264)
Enzyme-synthesized highly branched maltodextrins have slow glucose generation at the mucosal α-glucosidase level and are slowly digestible in vivo. [PDF]
PLoS ONE, 2013 For digestion of starch in humans, α-amylase first hydrolyzes starch molecules to produce α-limit dextrins, followed by complete hydrolysis to glucose by the mucosal α-glucosidases in the small intestine.
Byung-Hoo Lee +9 more
doaj +1 more source
Beta-glucosidase 1 (GBA1) is a second bile acid β-glucosidase in addition to β-glucosidase 2 (GBA2). Study in β-glucosidase deficient mice and humans [PDF]
Biochemical and Biophysical Research Communications, 2012 Beta-glucosidase 1 (GBA1; lysosomal glucocerebrosidase) and β-glucosidase 2 (GBA2, non-lysosomal glucocerebrosidase) both have glucosylceramide as a main natural substrate. The enzyme-deficient conditions with glucosylceramide accumulation are Gaucher disease (GBA-/- in humans), modelled by the Gba-/- mouse, and the syndrome with male infertility in ...
Harzer, Klaus +6 more
openaire +3 more sources
Conductive Hydrogels for Exogenous Sensing and Cell Fate Control
Advanced Materials, EarlyView.We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar +15 more
wiley +1 more source
Structural analysis of rice Os4BGlu18 monolignol β-glucosidase.
PLoS ONE, 2021 Monolignol glucosides are storage forms of monolignols, which are polymerized to lignin to strengthen plant cell walls. The conversion of monolignol glucosides to monolignols is catalyzed by monolignol β-glucosidases.
Supaporn Baiya +3 more
doaj +1 more source
Advanced Science, EarlyView.Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu +12 more
wiley +1 more source
PLoS Neglected Tropical Diseases, 2016 It has long been thought that iminosugar antiviral activity is a function of inhibition of endoplasmic reticulum-resident α-glucosidases, and on this basis, many iminosugars have been investigated as therapeutic agents for treatment of infection by a ...
Andrew C Sayce +15 more
doaj +1 more source
Molecules, 2019 β-Glucosidases are enzymes with high importance for many industrial processes, catalyzing the last and limiting step of the conversion of lignocellulosic material into fermentable sugars for biofuel production.
Leon Sulfierry Corrêa Costa +7 more
doaj +1 more source
, 1993 *b-Glucosidases: Overview *b-Glycosidases in Plants: Substrate Specificity *b-Glucosidases, *b-Glucanases, and Xylanases: Their Mechanism of Catalysis A *b-Glucosidase from an Agrobacterium sp.: Structure and Biochemistry Deletion of the Trichoderma reesei *b-Glucosidase Gene, bgl11 Molecular Biology and Enzymology of Human Acid *b-Glucosidase The ...
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Mechanism of activation of glucocerebrosidase by CO-β-glucosidase (glucosidase activator protein) [PDF]
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1981 The nature of the stimulatory action of the protein 'coglucosidase' on glucocerebrosidase was investigated with the use of highly purified cofactor from bovine spleen, radioactive glucosyl ceramide and methylumbelliferyl-beta-glucoside. A complex between glucosidase and either substrate could not be detected under equilibrium and non-equilibrium ...
Berent, Susan L., Radin, Norman S.
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Climate Change Threatens Micronutrient Density of European Winter Wheat
Advanced Science, EarlyView.Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao +17 more
wiley +1 more source