Results 61 to 70 of about 39,507 (336)

Structural analysis of rice Os4BGlu18 monolignol β-glucosidase.

PLoS ONE, 2021
Monolignol glucosides are storage forms of monolignols, which are polymerized to lignin to strengthen plant cell walls. The conversion of monolignol glucosides to monolignols is catalyzed by monolignol β-glucosidases.
Supaporn Baiya, Salila Pengthaisong, Sunan Kitjaruwankul, James R Ketudat Cairns   +3 more
doaj   +1 more source

Comparative Investigations on Different β-Glucosidase Surrogate Substrates

Fermentation, 2022
β-glucosidases are hydrolyzing enzymes which can release many aroma-active compounds from their glycoside form. Several yeasts produce these enzymes and thus are applied during the wine production process.
Felix Marcel Rainer Graf, Markus Buchhaupt   +1 more
doaj   +1 more source

Molecular Aggregates of Wheat Starch–Protein Systems: Structural Disruption and Engineered Digestibility via Non‐Covalent Synergy

Aggregate, EarlyView.
This study combines molecular dynamics simulations and multi‐scale experiments to decode how wheat proteins (globulin, gliadin, and glutelin) form non‐covalent networks with starch, reducing structural order, and slowing enzymatic hydrolysis. These findings provide a blueprint for tailoring starch‐based foods with controlled glycemic response ...
Cuihong Dai, Dongling Qiao, Bowen Li, Fengwei Xie, Binjia Zhang   +4 more
wiley   +1 more source

Identification and Characterization of a Novel Biallelic SLC12A2 Variant Associated With Kilquist Syndrome (OMIM #619080)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study presents the case of a child with multiple congenital anomalies, severe hypotonia, and profound bilateral sensorineural hearing loss. Functional bioenergetic assessments showed no significant mitochondrial respiratory defects, and riboflavin (Rf) status evaluation excluded a deficiency in Rf transporters as a cause of hearing loss ...
Piero Leone, Alessia Nisco, Luciana de Gennaro, Maria Tolomeo, Elisa Lorefice, Giuseppe Petrosillo, Silvia Russo, Donatella De Giovanni, Claudia Rita Catacchio, Francesca Romana Lepri, Mario Ventura, Simonetta Simonetti, Albina Tummolo, Maria Barile   +13 more
wiley   +1 more source

Enzyme-synthesized highly branched maltodextrins have slow glucose generation at the mucosal α-glucosidase level and are slowly digestible in vivo. [PDF]

PLoS ONE, 2013
For digestion of starch in humans, α-amylase first hydrolyzes starch molecules to produce α-limit dextrins, followed by complete hydrolysis to glucose by the mucosal α-glucosidases in the small intestine.
Byung-Hoo Lee, Like Yan, Robert J Phillips, Bradley L Reuhs, Kyra Jones, David R Rose, Buford L Nichols, Roberto Quezada-Calvillo, Sang-Ho Yoo, Bruce R Hamaker   +9 more
doaj   +1 more source

Harnessing the multidimensional bioactivity of Chaetomorpha aerea: Integrative phytochemical profiling with in vitro, in vivo, and in silico insights

Animal Models and Experimental Medicine, EarlyView.
This study revealed the antioxidant, anti‐inflammatory, and antidiabetic potentials of the seaweed Chaetomortpha aerea using in vitro, in vivo, and in silico approaches along with phytochemical analysis using gas chromatography–mass spectrometry. ADME/T analysis was also carried out to confirm drug likeness and toxicity prediction.
Md. Mahmudul Hasan, Md. Abdul Alim, Md. Safayat Hossen Momen, Md. Shahidul Islam, Sajjad Hossen Chowdhury, Mohammad Rashed, Fahmina Hoque, S. M. Moazzem Hossen   +7 more
wiley   +1 more source

Analysis of the Developmental Regulation of the Cyanogenic Compounds in Seedlings of Two Lines of \u3cem\u3eLinum usitatissimum\u3c/em\u3e L. [PDF]

, 2003
The developmental profiles and tissue distribution of the four cyanogenic compounds in seedlings of two developmentally contrasting inbred lines of flax (Linum usitatissimum L.) were examined using HPLC.
Fieldes, Mary Ann, Krech, M.J.
core   +1 more source

Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk, Neslihan Balci, Osman Nuri Aslan, Erbay Kalay   +3 more
wiley   +1 more source

Biochemical characterization of digestive carbohydrases from Xanthogaleruca luteola and inhibition of its α-amylase by inhibitors extracted from the common bean [PDF]

, 2011
Xanthogaleruca luteola Müll. (Col.: Chrysomelidae) is a major urban insect pest on elm trees in Iran. Digestion in the alimentary canal of the elm leaf beetle is facilitated by some carbohydrases which are responsible for the digestion of ...
Ghadamyari Mohammad, Moghadam Mahdavi Maryam, Saiidi Fetemeh, Sharifi Mahbobeh   +3 more
core   +1 more source

Honokiol as an α-glucosidase inhibitor

Frontiers in Pharmacology
Honokiol, a naturally occurring compound from Magnolia obovata Thunb., has many biological activities, but its anti-α-glucosidase activity is still unclear. Therefore, we determined its inhibitory effects against α-glucosidase. Activity assays showed that honokiol was a reversible mixed-type inhibitor of α-glucosidase, and its IC50 value was 317.11 ...
Hua Zhu, Xin Zhong
openaire   +3 more sources