Glucosylceramides and kidney disease
Glucosylceramides are part of the wider family of glycosylceramides. Glucosylceramide synthase catalyzes the incorporation of a single glucose residue into ceramide to yield glucosylceramide. Glucosylceramide is known as a precursor for globotriaosylceramide (Gb3). In the cell membrane, Gb3 acts a receptor for verotoxin and plays a key role in allowing
Ortiz,Alberto +1 more
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Drosophila Glucosylceramide Synthase [PDF]
Ayako Kohyama-Koganeya +6 more
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Transport and Translocation of Glucosylceramide
Glycosphingolipids (GSL) are important determinants of the functional organization of cellular membranes. They are controlled by the spatial organization of their metabolism and by specificity in transport. The aim of this thesis was to gain insight into the function of membrane lipids by learning more about their localization and intracellular ...
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The mTORC2 subunit RICTOR drives breast cancer progression by promoting ganglioside biosynthesis through transcriptional and epigenetic mechanisms. [PDF]
Ansari MN +23 more
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Konjac Ceramide Induces Semaphorin 3A Expression via the MAPK/AP-1 Signaling Axis and RORα in Normal Human Epidermal Keratinocytes. [PDF]
Fujita M +5 more
europepmc +1 more source
Modest improvement of metabolic and behavioral deficits with long-term ambroxol treatment in a Pink1<sup>-/-</sup>SNCA<sup>A53T</sup> double mutant mouse model of Parkinson's disease. [PDF]
Franck L +10 more
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Effects of a Reprometabolic Syndrome-Inducing Eucaloric High-Fat Diet on Insulin Sensitivity, Body Composition, the Lipidome, and the Microbiome. [PDF]
Schauer IE +8 more
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Elevated hexosylceramides in Parkinson's disease cause gene upregulations in neurons mimicking responses to pathogens. [PDF]
Franck L +12 more
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The impact of C. elegans ceramide glucosyltransferase enzymes on the beneficial effects of B. subtilis lifespan. [PDF]
Arvin CL +4 more
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