Results 71 to 80 of about 1,898 (179)

Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers[S]

Journal of Lipid Research, 2012
This report details the lipid composition of nascent HDL (nHDL) particles formed by the action of the ATP binding cassette transporter A1 (ABCA1) on apolipoprotein A-I (apoA-I). nHDL particles of different size (average diameters of ∼12, 10, 7.5, and
Mary G. Sorci-Thomas, John S. Owen, Brian Fulp, Shaila Bhat, Xuewei Zhu, John S. Parks, Dharika Shah, W. Gray Jerome, Mark Gerelus, Manal Zabalawi, Michael J. Thomas   +10 more
doaj   +1 more source

Measles virus reprograms CD4+ T-cell sphingolipid and fatty acid metabolism to facilitate infection

Frontiers in Cell and Developmental Biology
IntroductionCD150-positive (CD150+) lymphocytes are the primary targets of measles virus (MV) infection during the acute phase. The depletion of infected CD150+ memory cells leads to a profound suppression of immune memory, resulting in increased ...
Maria Fernanda Grijalva Yépez, Yann Loïc Cordes, Agnes Fekete, Fabian Schumacher, Burkhard Kleuser, Elita Avota   +5 more
doaj   +1 more source

Permeability Barrier and Microstructure of Skin Lipid Membrane Models of Impaired Glucosylceramide Processing

Scientific Reports, 2017
Ceramide (Cer) release from glucosylceramides (GlcCer) is critical for the formation of the skin permeability barrier. Changes in β-glucocerebrosidase (GlcCer’ase) activity lead to diminished Cer, GlcCer accumulation and structural defects in SC lipid ...
Michaela Sochorová, Klára Staňková, Petra Pullmannová, Andrej Kováčik, Jarmila Zbytovská, Kateřina Vávrová   +5 more
doaj   +1 more source

Thematic review series: Skin Lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis

Journal of Lipid Research, 2007
The permeability barrier is required for terrestrial life and is localized to the stratum corneum, where extracellular lipid membranes inhibit water movement.
Kenneth R. Feingold
doaj   +1 more source

Deficiency in NPC2 results in disruption of mitochondria-late endosome/lysosomes contact sites and endo-lysosomal lipid dyshomeostasis

Scientific Reports
Dysfunction of the endo-lysosomal intracellular Cholesterol transporter 2 protein (NPC2) leads to the onset of Niemann–Pick Disease Type C (NPC), a lysosomal storage disorder.
Raffaele Pastore, Lihang Yao, Nathan Hatcher, Martin Helley, Janet Brownlees, Radha Desai   +5 more
doaj   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models

Scientific Reports
The EGFR tyrosine kinase inhibitor osimertinib has been approved for the first-line treatment of EGFR-mutated Non-Small Cell Lung Cancer (NSCLC) patients. Despite its efficacy, patients develop resistance.
Silvia La Monica, Federica Vacondio, Kamal Eltayeb, Alessio Lodola, Francesco Volta, Martina Viglioli, Francesca Ferlenghi, Francesca Galvani, Maricla Galetti, Mara Bonelli, Claudia Fumarola, Andrea Cavazzoni, Lisa Flammini, Michela Verzè, Roberta Minari, Pier Giorgio Petronini, Marcello Tiseo, Marco Mor, Roberta Alfieri   +18 more
doaj   +1 more source

Characterization of lipid composition and nutritional quality of yak ghee at different altitudes: A quantitative lipidomic analysis

Food Chemistry: X
Efficient and comprehensive analysis of lipid profiles in yak ghee samples collected from different elevations is crucial for optimal utilization of these resources. Unfortunately, such research is relatively rare. Yak ghee collected from three locations
Feiyan Yang, Xin Wen, Siwei Xie, Xudong He, Guangfan Qu, Xueying Zhang, Shuguo Sun, Zhang Luo, Zhendong Liu, Qinlu Lin   +9 more
doaj   +1 more source