Results 21 to 30 of about 25,775 (147)

Streptococcus mutans biofilm inhibition using antisense oligonucleotide to glucosyltransferases B and C

Acta Medica Lituanica, 2015
Background. Biofilm formation by Streptococcus mutans bacteria on teeth leads to dental caries, which still remains one of the most prevalent human diseases strongly related to increase of dietary sucrose consumption in modern society.
Povilas Kalesinskas, Tomas Kačergius, Arvydas Ambrozaitis, Ryo Jimbo, Dan Ericson   +4 more
doaj   +1 more source

ISOLATION AND PURIFICATION OF GLUCOSYLTRANSFERASE FROM MUTANS STREPTOCOCCUS SOBRINUS (SEROTYPE G) LOCAL ISOLATE

The Iraqi Journal of Medical Sciences, 2016
Background: Glucosyltransferase is an extracellular enzyme produced by mutans streptococci responsible for polymerizing the glucose moiety of sucrose to form glucan.
Nada H. Al-Mudallal, Essam F. Al-Jumaily, Nidhal Abdul Muhymen, Abd Al- Wahid Al-Shaibany   +3 more
doaj   +6 more sources

Enzymatic Synthesis of Modified Alternaria Mycotoxins Using a Whole-Cell Biotransformation System

Toxins, 2020
Reference standards for Alternaria mycotoxins are rarely available, especially the modified mycotoxins alternariol-3-glucoside (AOH-3-G), alternariol-9-glucoside (AOH-9-G), and alternariol monomethylether-3-glucoside (AME-3-G).
Sophie Scheibenzuber, Thomas Hoffmann, Isabelle Effenberger, Wilfried Schwab, Stefan Asam, Michael Rychlik   +5 more
doaj   +1 more source

Modulation of biofilm exopolysaccharides by the Streptococcus mutans vicX gene

Frontiers in Microbiology, 2015
The cariogenic pathogen Streptococcus mutans effectively utilizes dietary sucrose for the synthesis of exopolysaccharide, which act as a scaffold for its biofilm, thus contributing to its pathogenicity, environmental stress tolerance, and antimicrobial ...
Lei eLei, Yingming eYang, Mengying eMao, Hong eLi, Meng eLi, Yan eYang, Jiaxin eYin, Tao eHu   +7 more
doaj   +1 more source

Molecular Cloning and Functional Characterization of a Novel (Iso)flavone 4',7-O-diglucoside Glucosyltransferase from Pueraria lobata

Frontiers in Plant Science, 2016
Pueraria lobata roots accumulate a rich source of isoflavonoid glycosides, including 7-O- and 4'-O-mono-glucosides, and 4',7-O-diglucosides, which have numerous human health benefits.
Xin eWang, Rongyan eFan, Jia eLi, Changfu eLi, Yansheng eZhang   +4 more
doaj   +1 more source

Synergistic inhibitory activity of Glycyrrhizae Radix and Rubi Fructus extracts on biofilm formation of Streptococcus mutans

BMC Complementary Medicine and Therapies, 2023
Background Streptococcus mutans is a bacterium that causes oral diseases. Plaque, a biofilm produced by S. mutans and other bacteria, makes it difficult to remove cariogenic oral microorganisms, including biofilm producers.
Youngseok Ham, Tae-Jong Kim
doaj   +1 more source

Muntingia calabura L Leaves Extract Inhibits Glucosyltransferase Activity of Streptococcus mutans

Journal of Dentistry Indonesia, 2014
Jamaican cherry (Muntingia calabura L.) is one type of plants that used by Indonesians as traditional medicine. Muntingia calabura L. leaves contain tannins, flavonoids, and polyphenolics that are believed to have capability as antibacterial agent.
Rina Isnarianti, Ivan A. Wahyudi, Rini M. Puspita   +2 more
doaj   +1 more source

Receptor Binding Domains of TcdB from Clostridioides difficile for Chondroitin Sulfate Proteoglycan-4 and Frizzled Proteins Are Functionally Independent and Additive

Toxins, 2020
Toxin B (TcdB) produced by Clostridioides difficile is a main pathogenicity factor that affects a variety of different cell types within the colonic mucosa. TcdB is known to utilize frizzled-1,2,7 and chondroitin sulfate proteoglycan-4 (CSPG4) as protein
Daniel Henkel, Helma Tatge, Dennis Schöttelndreier, Liang Tao, Min Dong, Ralf Gerhard   +5 more
doaj   +1 more source

The Effect of Recombinant Tags on Citrus paradisi Flavonol-Specific 3-O Glucosyltransferase Activity

Plants, 2020
Recombinant tags are used extensively in protein expression systems to allow purification through IMAC (Immobilized Metal Affinity Chromatography), identification through Western blot, and to facilitate crystal formation for structural analysis.
Aaron S. Birchfield, Cecilia A. McIntosh   +1 more
doaj   +1 more source

Cell wall glycosyltransferase of Streptococcus mutans impacts its dissemination to murine organs

Infection and Immunity
Streptococcus mutans, a cariogenic bacterium in humans, is associated with systemic disorders. Its cariogenic factors include glucosyltransferases (GTFs) and the glycosyltransferase rhamnose–glucose polysaccharide I (RgpI), which is involved in cell wall
Tomomi Hashizume-Takizawa, Taiki Ando, Ayaka Urakawa, Kazuhiro Aoki, Hedenobu Senpuku   +4 more
doaj   +1 more source