Results 31 to 40 of about 1,677 (151)

Posttranslational Modifications of p62/SQSTM1 in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang, Xin Jiang, Runing Qiu, Chandra Sugiarto Wijaya, Miaoqin Chen, Jin Wang, Liyuan Zhu, Hongchuan Jin, Lifeng Feng   +8 more
wiley   +1 more source

Clarification and reprogramming of glucose and xylose metabolism in Sphingomonas sanxanigenens for efficient sanxan biosynthesis

mLife, Volume 5, Issue 5, Page 582-596, October 2026.
Abstract Currently, the production of high‐value chemicals from natural lignocellulose is of great significance for a circular economy. In this study, a robust platform was developed based on Sphingomonas sanxanigenens NXdP, which co‐utilizes glucose and xylose to synthesize polysaccharide sanxan, for efficient bioconversion of lignocellulose‐derived ...
Yue Ming, Zhuangzhuang Shi, Yiting Lin, Jue Li, Weilong Wang, Wei Sha, Guoqiang Li, Mengmeng Wu, Ting Ma   +8 more
wiley   +1 more source

Patterns of Functional Redundancy and Anaerobic Metabolic Potential Characterise the Skin Microbiome of a Critically Endangered Sawfish

Environmental Microbiology, Volume 28, Issue 10, October 2026.
The largetooth sawfish skin supports a distinct microbiome enriched in anaerobic metabolic and dormancy potential, consistent with microbial persistence under low‐oxygen conditions. Greater among‐individual taxonomic variability coupled with functional redundancy potential supports a lottery‐like mechanism of microbiome assembly.
Michael P. Doane, Belinda Martin, Emma Kerr, Elizabeth A. Dinsdale, Malak Malak Rangers, Leonardo Guida, Pete M. Kyne   +6 more
wiley   +1 more source

Ya‐Jie‐Sha‐Ba Decoction Regulates Arachidonic Acid Metabolism to Treat Alcohol‐Associated Liver Disease by Activating PPARα–CYP4A14 Axis: Insights From Multi‐Omics Analysis and Experimental Validations

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Ya‐Jie‐Sha‐Ba decoction (YJSB), a traditional Dai medicinal formulation, has been widely used by the Dai ethnic group and has shown efficacy in alleviating alcohol‐associated liver disease (ALD). However, the molecular mechanism of YJSB in the management of ALD remains unclear.
Dehong Ma, Xia Chen, Huixian Dao, Hongyu Deng, Yingcheng Guo, Hui Yang, Yuanyuan Chen, Congmei Zhang, Yuan Long, Weibo Wen, Yinghong Zhao, Huantian Cui   +11 more
wiley   +1 more source

Insights Into the Origin and Local Adaptation Evolution of the Cultivated Sesame With Telomere‐to‐Telomere High‐Quality Genome

Plant Biotechnology Journal, Volume 24, Issue 10, Page 5372-5391, October 2026.
ABSTRACT Sesame (Sesamum indicum L., 2n = 26) is one of the oldest oilseed crops and is often called the ‘queen of oilseeds’ due to its high content of unsaturated fatty acids and natural antioxidants. Despite its long history, the origin and global spread of cultivated sesame remain unresolved.
Weifei Yang, Hengchun Cao, Hui Guo, Hongmei Miao, Guiting Li, Yinghui Duan, Ming Ju, Qiuzhen Tian, Qin Ma, Pengjie Chang, Zhanyou Zhang, Cong Mu, Xiaoxu Feng, Libin Wei, Weixiu Hou, Andrew H. Paterson, Haiyang Zhang   +16 more
wiley   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, Volume 13, Issue 51, 14 September 2026.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

Codeine toxicity via breast Milk: Can this occur and implications for opiate therapy in children

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3012-3016, September 2026.
Codeine is commonly used in combination analgesic products. The use of codeine during breastfeeding can rarely be associated with serious adverse effects related to genetic polymorphisms affecting codeine's metabolism and disposition. Clinicians treating infants of breastfeeding mothers should be aware of this rare but potentially serious complication.
Michael Rieder
wiley   +1 more source

Transport of lucifer yellow CH into plant vacuoles - evidence for direct energization of a sulphonated substance and implications for the design of new molecular probes

, 1997
Contrasting observations exist which indicate that in plants the fluorescent dye lucifer yellow CH (LYCH) either can be used as a tracer for endocytosis or as a substrate for an anion transporter located at the vacuolar membrane.
Enrico Martinoia, Markus Klein, Gottfried Weissenböck   +2 more
core   +1 more source

Stage‐Dependent Metabolic Reprogramming Drives a Self‐Organizing Microbial Network During Shanxi Aged Vinegar

Food Bioengineering, Volume 5, Issue 3, Page 342-358, September 2026.
Metabolic shifts from growth to stress adaptation in Shanxi aged vinegar fermentation link flavor maturation and microbial cooperation, and Lactobacillus and Acetobacter form a self‐organizing metabolic network through division of labor. ABSTRACT Acetic acid fermentation (AAF) is a vital stage in the production of Shanxi aged vinegar (SAV), during ...
Yanfang Wu, Jing Liu, Dantong Liu, Menglei Xia, Jia Song, Yu Zheng, Min Wang   +6 more
wiley   +1 more source

Enzymatic synthesis of novel substrates for the characterization of glucuronoyl esterases

, 2013
116 σ.Στην παρούσα διπλωματική εργασία μελετήθηκε η δράση της εστεράσης του γλυκουρονικού οξέος από το θερμόφιλο μύκητα Sporotrichum thermophile σε συνθετικά ανάλογα των φυσικών υποστρωμάτων και πιο συγκεκριμένα σε φαινυλεστέρες του γλυκουρονικού οξέος.
Κατσίμπουρας, Κωνσταντίνος Η., Katsimpouras, Constantinos E.   +1 more
core   +1 more source