Interactions between bacteria and the extracellular matrix are a prerequisite for colonisation and infection. Phylogenetically diverse M proteins of group A Streptococcus (GAS) can selectively bind sulfated glycosaminoglycans with high affinity. M protein‐mediated recruitment of chondroitin sulfate and dermatan sulfate was shown to increase GAS ...
Tahnee B.‐D. McEwan+8 more
wiley +1 more source
Summary One‐carbon (C1) metabolism, centered on the universal methyl donor S‐adenosyl methionine (SAM), plays critical roles in biosynthesis, redox regulation, and stress responses across plants and microbes. A recently proposed photosynthetic C1 pathway links SAM methyl groups directly to RuBisCO‐mediated CO2 assimilation and integrates with nitrogen ...
Kolby J. Jardine+6 more
wiley +1 more source
Unexpected Diastereomer Formation and Interconversions in Cyclohexane-1,2-diacetal Derivatization of a Glucuronic Acid Thioglycoside. [PDF]
Alharthi FA+5 more
europepmc +1 more source
Summary Biofortification of staple crops is a sustainable strategy to deliver essential micronutrients to impoverished populations in developing countries. Banana is a highly valued crop consumed by over 75% of Ugandans. However, the starchy green cooking bananas have very low levels of pro‐vitamin A (PVA) and heavy dietary reliance on them has been ...
Stephen Buah+8 more
wiley +1 more source
The effect of manipulating glucuronic acid biosynthetic pathway in Bacillus subtilis strain on hyaluronic acid production. [PDF]
Afrasiabi S+4 more
europepmc +1 more source
Studies in detoxication. II. (a) The conjugation of isomeric 3-menthanols with glucuronic acid and the asymmetric conjugation of dl-menthol and dl-isomenthol in the rabbit. (b) d-isoMenthylglucuronide, a new conjugated glucuronic acid [PDF]
R. T. Williams
openalex +1 more source
Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana
Summary Transient expression in Nicotiana benthamiana offers a powerful and versatile platform for rapid production of complex specialized metabolites. Steroidal glycoalkaloids (SGAs) and steroidal saponins produced by members of the Solanaceae family are known for their diverse structures and activities including antimicrobial, anticancer, antiviral ...
Sachin A. Gharat+6 more
wiley +1 more source
Glucuronic acid metabolites of phenolic acids target AKT-PH domain to improve glucose metabolism. [PDF]
Gao J+6 more
europepmc +1 more source
Unveiling the catalytical roles of three glycosyltransferases in triterpenoid saponins in quinoa
Summary Saponins constitute a class of characteristic compounds within quinoa grains. In this study, metabolomic analysis identified 20 triterpene saponins, the majority of which were exclusively localized within the pericarp. Furthermore, three crucial glycosyltransferases were identified in quinoa.
Yiming Zhang+14 more
wiley +1 more source
Corrigendum to "Dysregulated glucuronic acid metabolism exacerbates hepatocellular carcinoma progression and metastasis through the TGFβ signalling pathway". [PDF]
Gao Q+11 more
europepmc +1 more source