Results 31 to 40 of about 33,038 (158)

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

FURIN induces vascular endothelial cell death and efferocytosis through enzymatic cleavage of thrombospondin‐1

The Journal of Physiology, EarlyView.
Abstract figure legend FURIN induces vascular endothelial cell (VEC) death and efferocytosis through enzymatic cleavage of thrombospondin‐1 (THBS1). FURIN interacts with THBS1 to induce VEC apoptosis and efferocytosis, resulting in increased endothelial permeability.
Runji Chen, Daifei Shen, Amandine Mahieux, Dedrick Song, Shiwan Wu, Xiaoxin Huang, Xu Yang, Kunwei Chen, David G. McVey, Elisa A. Liehn, Roshni R. Singaraja, Shu Ye   +11 more
wiley   +1 more source

Amides of glucuronic, galacturonic, and mannuronic acids

Journal of Research of the National Bureau of Standards, 1948
Heretofore the amides of glucuronic, galacturonic, and mannuronic acid were not known, and methods were not available for their preparation. It has now been found possible to obtain the amides of uronic acids from the corresponding 1-amino-uronamides by selective hydrolysis of the glycosylamino group.
H L, FRUSH, H S, ISBELL
openaire   +2 more sources

Chitosan‐induced modulation of secondary metabolism and stress tolerance in Salvia rosmarinus under combined drought and heat stress

Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 5989-6001, 15 August 2026.
Abstract BACKGROUND Abiotic stresses, particularly drought and elevated temperatures, negatively affect plant physiological and metabolic processes. This study investigated the effects of drought, heat, and combined stress on Salvia rosmarinus (rosemary), and evaluated foliar‐applied chitosan as a biostimulant.
Inês Mansinhos, Sandra Gonçalves, Raquel Rodríguez‐Solana, Efrén Pérez‐Santín, María I Fernández‐Marín, Emma Cantos‐Villar, Anabela Romano   +6 more
wiley   +1 more source

Apple Pomace Pectin for Gastroprotective Nutraceutical Delivery: Structure–Function Relationships and Nano/Microencapsulation Strategies for Gastric Ulcer Management

Food Frontiers, Volume 7, Issue 4, July 2026.
Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman, Shefali Arora, Parteek Prasher, Sukanya Chhetri, Pankaj Bhandari, William N. Setzer, Javad Sharifi‐Rad   +6 more
wiley   +1 more source

Contrasting CO2‐response strategies in Pardina lentils: Yield maximization in a commercial cultivar and seed composition adjustment in a landrace

Journal of the Science of Food and Agriculture, Volume 106, Issue 9, Page 5422-5436, July 2026.
Abstract BACKGROUND Assessing crop's responses to elevated carbon dioxide (eCO2) is crucial for global food security. This study examines the impact of eCO2 (700 μmol mol−1) on the cultivars of lentil (Lens culinaris), local Pardina Verde Rayada lentil (PVRL), and commercial Pardina lentil (PL) in terms of the productivity and nutritional composition ...
Mohammad Abdullah, Idoia Garmendia, Cristina Mallor, Nieves Goicoechea, Johann Martínez‐Lüscher   +4 more
wiley   +1 more source

The Effects of Glucuronic Acid on Acne Vulgaris

The Tohoku Journal of Experimental Medicine, 1956
1. The liver function tests revealed that the majority of patients with acne vulgaris showed the disturbance of liver function. 2. It was shown that the glucuronic acid administration yielded remarkably beneficial effects upon acne vulgaris. 3. The authors discussed why glucuronic acid highly efficacious on acne vulgaris was.
Tsukada, Susumu, Tanida, Tsunao, Aikawa, Atsunobu, Mihara, Junichiro   +3 more
openaire   +3 more sources

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

Mass Spectrometry Reviews, Volume 45, Issue 4, Page 829-850, July/August 2026.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song, HyunJi Lee, Youngshik Choe, Hyeyoung Lee   +3 more
wiley   +1 more source

Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering

Medicinal Research Reviews, Volume 46, Issue 4, Page 966-988, July 2026.
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo, Shinwon Kang, Jae Eun Yang, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Glucuronic acid is a novel source of pentosidine, associated with schizophrenia. [PDF]

Redox Biol, 2023
Toriumi K, Iino K, Ozawa A, Miyashita M, Yamasaki S, Suzuki K, Sugawa H, Tabata K, Yamaguchi S, Usami S, Itokawa M, Nishida A, Nagai R, Kamiguchi H, Arai M.   +14 more
europepmc   +1 more source