Results 101 to 110 of about 31,424 (230)

Self‐Immolative Systems in Diagnostic and Therapeutic Applications

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
Self‐Immolative Systems enable the precise, residue‐free release of active molecules, drugs, probes, or sensors, via cyclization or elimination, triggered by specific stimuli. Their versatility drives advances in drug delivery, diagnostics, nanotechnology, materials chemistry, and biosensing, offering chemists control over molecular activation and ...
Windbedema Prisca Ouédraogo   +2 more
wiley   +1 more source

Preservation of cell‐free RNA in percutaneous core‐needle biopsy specimens' supernatants from non‐small cell lung cancer improves genomic testing performance

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract This prospective single‐center study aimed to investigate whether preserving cell‐free ribonucleic acid (cfRNA) in specimens' supernatants (SS) obtained from percutaneous core‐needle biopsy (CNB) of non‐small cell lung cancer (NSCLC) can improve the performance of genomic testing.
Sheng Xu   +6 more
wiley   +1 more source

Investigations Into the Human Metabolism of Trestolone (7α‐Methyl‐19‐Nortestosterone)

open access: yesDrug Testing and Analysis, Volume 18, Issue 3, Page 341-353, March 2026.
As the known metabolites of 7α‐methyl‐19‐nortestosterone (MENT), M1 and M2, suffer from chromatographic issues under routine doping control conditions, the human metabolism of MENT was reinvestigated. From the numerous new metabolites detected, especially, M5 and M10 were identified as the most promising candidates to be implemented into routine ...
Thomas Piper   +2 more
wiley   +1 more source

Urinary and Plasma Profiles of Betamethasone and Triamcinolone Acetonide Following Intra‐Articular and Related Administrations

open access: yesDrug Testing and Analysis, Volume 18, Issue 3, Page 426-438, March 2026.
Intra‐articular and periarticular administrations of betamethasone and triamcinolone acetonide produce systemic effects, with compound‐ and route‐dependent profiles. The results support the MRLs in urine established by WADA and recommend increasing the washout period for betamethasone.
Sergi Coll   +8 more
wiley   +1 more source

Perinatal Gut Dysbiosis Reduces Milk Oligosaccharides via LPS‐Mediated Gut–Mammary Signaling in Mice

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
Maternal gut dysbiosis elevates Gram‐negative bacterial lipopolysaccharide (LPS), which enters circulation and accumulates in mammary tissue. This compromises the blood–milk barrier and suppresses key enzymatic genes, ultimately reducing milk oligosaccharide synthesis and potentially affecting neonatal gut microbiota through breastfeeding.
Man‐Lin Zhou   +9 more
wiley   +1 more source

Arachis hypogaea L. Root Extract Mitigates Testosterone Propionate‐Induced Benign Prostatic Hyperplasia in ICR Mice by Suppressing Inflammation, Androgen Receptors, and Dihydrotestosterone

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
In summary this study evaluated the protective effects of Arachis hypogaea L. root extract (AHRE) against testosterone propionate (TP)‐induced benign prostatic hyperplasia (BPH) in ICR mice. AHRE was prepared and administered in varying doses (100, 200, 300 mg/kg BW) alongside TP, with finasteride as a positive control.
Samee‐Ullah   +9 more
wiley   +1 more source

Beyond a Conduit: The Evolution of Functional Biliary Stents From Active Intervention to Enabling Platforms

open access: yesiNew Medicine, Volume 2, Issue 1, March 2026.
This review traces the evolution of functional biliary stents, outlining the paradigm shift from “active intervention” strategies that target stent failure to next‐generation “enabling platforms.” These platforms leverage biodegradable materials, 3D/4D printing, and smart sensors to achieve personalized, regenerative, and theranostic solutions ...
Muhan Li   +4 more
wiley   +1 more source

Understanding the Role of Deconjugation of Phase II Metabolites in Wastewater: Implications for Wastewater-Based Epidemiology. [PDF]

open access: yesEnviron Sci Technol
Elliss H   +9 more
europepmc   +1 more source

An Optimised Protocol for Faba Bean (Vicia faba L.) Tissue Culture and Transformation

open access: yesLegume Science, Volume 8, Issue 1, March 2026.
ABSTRACT Faba bean (Vicia faba L.) is an important legume that contributes to agricultural sustainability through nitrogen fixation and offers substantial nutritional benefits. Nonetheless, its genetic enhancement has been constrained by challenges associated with tissue culture and transformation.
Md Mamunur Rashid   +7 more
wiley   +1 more source

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