Results 111 to 120 of about 43,079 (209)
New Phytologist, Volume 252, Issue 4, Page 1526-1544, November 2026.Proposed model of ZmSPL12‐mediated drought resistance through auxin regulation. Summary Climate change‐induced drought increasingly threatens global maize production. Drought‐adaptive root plasticity in maize depends on auxin signaling, yet how auxin homeostasis is dynamically tuned in response to water deficit remains unclear.
Hua Xu +18 more
wiley +1 more source
Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants
Advanced Science, Volume 13, Issue 55, 5 October 2026.This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley +1 more source
Chemistry – A European Journal, Volume 32, Issue 37, 1 October 2026.Integrin αVβ3‐targeting small‐molecule drug conjugates (SMDCs) were synthesized by conjugating a cryptophycin payload through a neutrophil elastase‐cleavable NPV‐PABC linker. RGD peptidomimetic and linker epimers served as controls for targeting and enzymatic cleavage, and the resulting conjugates displayed subnanomolar cytotoxicity in vitro.
Dominic Seißenschmidt +3 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 871-889, October 2026.The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó +7 more
wiley +1 more source
Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li +6 more
wiley +1 more source
β-Glucuronidase and Arylsulphatase in some Marine Invertebrates of the Canadian Atlantic Coast
, 1970 β-Glucuronidase and arylsulphatase activity in the digestive gland tissue varied widely among 15 invertebrate species examined. β-Glucuronidase activity was highest in three algae-feeding species of Gastropoda, Littorina littorea, L.
Doris Fraser Hiltz, Thérèse E. Lightle
core +1 more source
Drug Testing and Analysis, Volume 18, Issue 10, Page 1321-1327, October 2026.A validated LC‐HRMS/MS method enabled the first quantitative determination of the LGD‐4033 long‐term metabolite (M5‐b) in urine following controlled micro‐dose administration. The generated urinary reference data support the interpretation of adverse analytical findings and anti‐doping result management. ABSTRACT Selective androgen receptor modulators (
Panagiotis Sakellariou +7 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 10, October 2026.Selected orally administered probiotics and functional‐food interventions may alter gut microbial ecology and intestinal barrier function. Microbiota‐derived metabolites, microbial components, and endocrine signals—including short‐chain fatty acids, bile acids, tryptophan metabolites, and lipopolysaccharide—may influence systemic immune, metabolic, and
Meiqi Chen +6 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 10, October 2026.The capitula of Coreopsis tinctoria Nutt. polyphenol extract (CCTE) attenuate CUMS‐induced depressive‐like behaviors and hippocampal neuronal damage in mice. Three flavonoid aglycones—okanin, isookanin, and taxifolin—cross the blood–brain barrier and synergistically inhibit MAO‐A, restoring serotonergic tone; concurrently, CCTE normalizes HPA‐axis ...
Haixia Han +8 more
wiley +1 more source