Results 131 to 140 of about 63,621 (270)
Drug Testing and Analysis, Volume 18, Issue 5, Page 669-677, May 2026.Bioactivation and metabolism of MDMA prodrugs: MDMA‐Trp, MDMA‐Lys, MDMA‐Gly showed unique urine screening targets only for MDMA‐Trp, while biomarkers for MDMA‐Lys and MDMA‐Gly consisted of MDMA and known MDMA metabolites. Conversion of amino acid prodrugs to MDMA in pHLS9, zebrafish embryos, and humans. ABSTRACT 3,4‐Methylenedioxymethamphetamine (MDMA)
Simon K. Wellenberg +6 more
wiley +1 more source
Drug Testing and Analysis, Volume 18, Issue 5, Page 678-689, May 2026.The micro‐scale synthesis of the six out of eight possible tetrahydro‐methyltestosterone sulfate metabolites was performed, and the synthesized materials were used as analytical standards. The analysis of post‐administration sample extracts from methyltestosterone excretion studies against these standards provides further experimental proof for their ...
Yiannis S. Angelis +3 more
wiley +1 more source
Validation of Coffee seed promoter in Nicotiana tabacum [PDF]
, 2010 Promoters that restrict transgenic expressions in a specific organ or tissue and, at a certain stage of plant development or in response to stress are extremely desirable for the improvement of agronomic species by transgenesis.
Andrade, Alan Carvalho +5 more
core
Resveratrol for Cancer Radio‐Sensitization: Ready for Prime Time or Future Perspective
Food Science &Nutrition, Volume 14, Issue 5, May 2026.Resveratrol exerts antioxidant and anti‐inflammatory effects by reducing reactive oxygen species and suppressing NF‐κB and JAK/STAT signaling pathways. It modulates metabolic signaling through AMPK‐dependent inhibition of mTOR, influencing cell survival and inflammatory responses.
Maryam Fallah +7 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background and Aims Dysbiosis is the substitution of the normal gut flora with a dysfunctional array of organisms that influences the outcome of multiple inflammatory pathways, contributing to systemic inflammation and various disease states. It has historically been understudied, with outcomes that may directly or indirectly cause pathologies.
Srijanjali Balagoni +7 more
wiley +1 more source
Journal of Applied Toxicology, Volume 46, Issue 5, Page 1679-1686, May 2026.ABSTRACT Acephate is an organophosphate insecticide widely used. This pesticide can be metabolized into methamidophos, a molecule highly toxic. Both have demonstrated the ability to promote serious toxic effects on nontarget organisms and have been identified in surface waters around the world. Therefore, it is important to understand their behavior in
Mariana Laiz Silva de Lima +3 more
wiley +1 more source
JGH Open, Volume 10, Issue 5, May 2026.ABSTRACT The gut microbiota is a dynamic community of bacteria, viruses, fungi, and archaea that plays a pivotal role in regulating host immunity, metabolism, and systemic homeostasis. Dysbiosis, characterized by an imbalance in the microbial composition, is being increasingly recognized as a contributor not only to gastrointestinal cancers but also to
Rishi Chowdhary +8 more
wiley +1 more source
Biotecnología Vegetal, 2003 The present work describes the behavior of four rice explants: coleoptiles, embryogenic calli, earliest calli and mature embryos, in genetic transformation via Agrobacterium tumefaciens, applying the protocol established for cuban rice cultivar in our ...
Maylin Pérez +4 more
doaj
Sample Preparation and Separation of Lignans by Liquid Chromatography
Journal of Separation Science, Volume 49, Issue 5, May 2026.ABSTRACT Lignans are important phytochemicals found mostly in the resins of coniferous trees, but are also introduced into human diets through foods such as sesame seeds and extra‐virgin olive oil. They are pharmacologically interesting mainly because of their antioxidant activities, and they have also been shown to have cytotoxic and antimicrobial ...
Miikka Paloluoto, Susanne K. Wiedmer
wiley +1 more source
Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies
MedComm, Volume 7, Issue 5, May 2026.Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang +8 more
wiley +1 more source