Results 101 to 110 of about 63,621 (270)

Rooting Conifer Genetic Research: An Accessible and Efficient Transformation System

Plant Biotechnology Journal, EarlyView.
ABSTRACT Conifers serve as the cornerstone of global forest ecosystems, yet their genetic transformation faces notorious challenges. To overcome the intrinsic resistance of conifer adventitious roots to Agrobacterium/Rhizobium‐mediated transformation, we systematically and iteratively engineered the binary vector by introducing chimeric Ri plasmid ...
Jing‐Jing Li, Yi‐Mei Zhao, Jia‐Fan Liu, Chen‐He Li, Hui Zhang, Yi‐Tong Song, Quan Zuo, Pei‐Yi Wang, Kai Gao, Dong Meng, Shi‐Hui Niu   +10 more
wiley   +1 more source

Ethylene Response of Plum ACC Synthase 1 (ACS1) Promoter is Mediated through the Binding Site of Abscisic Acid Insensitive 5 (ABI5). [PDF]

, 2019
The enzyme 1-amino-cyclopropane-1-carboxylic acid synthase (ACS) participates in the ethylene biosynthesis pathways and it is tightly regulated transcriptionally and post-translationally.
Blumwald, Eduardo, Farcuh, Macarena, Feng, Jianrong, Qin, Qiaoping, Sadka, Avi, Shlizerman, Lyudmila, Toubiana, David, Zhang, Yunting   +7 more
core   +1 more source

Inhibitory Effects of Baicalein Derived from Japanese Traditional Herbal Medicine on SN-38 Glucuronidation

Journal of Pharmacy & Pharmaceutical Sciences, 2018
Purpose: The chemotherapeutic agent irinotecan is hydrolyzed to its active form SN-38 by human carboxyesterases, but SN-38 is converted into the inactive form SN-38G by hepatic UDP-glucuronosyltransferases (UGTs).
Takashi Satoh, Ayaka Igarashi, Misaki Tanno, Koki Yamada, Natsuko Takahashi-Suzuki, Kazuhiro Watanabe   +5 more
doaj   +1 more source

Knocking Out Two Polyphenol Oxidase Genes Significantly Improves Recombinant Protein Purification in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
ABSTRACT Efficient purification remains a key technical challenge affecting the recovery efficiency of recombinant proteins in plant‐based systems. Complex metabolites, particularly polyphenols, often cause recombinant protein aggregation during purification.
Hai‐Ping Diao, Hui‐Xin Meng, Xue‐Jiao Xu, Zeng‐Lin Zhang, Jian‐Feng Zhang, Yong‐Feng Guo, Inhwan Hwang, Shi‐Jian Song   +7 more
wiley   +1 more source

The Hepatocellular Hypoxia Criteria:2’Nitroimidazole Effect on Hepatocyte Carbohydrate Metabolizing Enzymes [PDF]

, 2008
Aim: to understand the 2’-nitroimidazole induced hypoxia and liver cell interaction, we proposed a “Hapatocellular Hypoxia Criteria”.
Rakesh Sharma
core   +1 more source

Agrobacterium-Mediated Stable Transformation of Medicinal Plant Andrographis paniculata Callus Expressing β-glucuronidase (GUS) Gene

Indonesian Journal of Biotechnology, 2015
This study was carried out to establish a stable genetic transformation in callus culture of Andrographispaniculata mediated by Agrobacterium tumefaciens. The leaf disks of A. paniculata were infected with A.
Erly Marwani, Agustina Tangapo, Fenny Martha Dwivany   +2 more
doaj  

Molecular Insights Into β‐Glucuronidase Inhibition by Alhagi Graecorum Flavonoids: A Computational and Experimental Approach

ChemistryOpen
In this study, we aimed to investigate the inhibitory mechanisms of β‐glucuronidase by flavonoids derived from Alhagi graecorum through both experimental and computational approaches.
Dr. Emadeldin M. Kamel, Saleh Maodaa, Esam M. Al‐Shaebi, Al Mokhtar Lamsabhi   +3 more
doaj   +1 more source

Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study

Journal of Translational Medicine, 2012
Background High systemic estrogen levels contribute to breast cancer risk for postmenopausal women, whereas low levels contribute to osteoporosis risk. Except for obesity, determinants of non-ovarian systemic estrogen levels are undefined.
Flores Roberto, Shi Jianxin, Fuhrman Barbara, Xu Xia, Veenstra Timothy D, Gail Mitchell H, Gajer Pawel, Ravel Jacques, Goedert James J   +8 more
doaj   +1 more source

The Advantaged Salt Inducible Suaeda salsa SsNRT2.5 and Its Promoter Significantly Enhance Nitrate Transport Efficiency and Salt Tolerance in Transgenic Arabidopsis and Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Efficient nitrogen (N) uptake is critical for crop yield, but soil salinization inhibits plant nitrogen acquisition. In this study, the nitrate (NO3−) transporter gene SsNRT2.5 and its promoter from the halophyte Suaeda salsa was investigated to elucidate the functional role in NO3− transport under salinity and low NO3−–N conditions.
Ranran Liu, Chenyang Li, Runtai Zhao, Congcong Song, Yan Zhou, Ruxin Zhao, Na Sui, Lei Wang, Jie Song   +8 more
wiley   +1 more source

Use of the KlADH4 promoter for ethanol-dependent production of recombinant human serum albumine in Kluyveromyces lactis [PDF]

, 1999
KlADH4 is a gene of Kluyveromyces lactis encoding a mitochondrial alcohol dehydrogenase activity which is specifically induced by ethanol. The promoter of this gene was used for the expression of heterologous proteins in K.
CRISA A., FALCONE, Claudio, FLEER R., JUNG G., MAZZONI, Cristina, SALIOLA, Michele, SOLIMANDO N.   +6 more
core