Results 81 to 90 of about 38,854 (228)

The role of human microbiota in breast cancer pathogenesis and treatment

iMeta, EarlyView.
The human microbiota contributes to breast cancer pathogenesis and treatment response through interactions involving the oral, gut, and breast microbial niches. (Left) Multi‐site dysbiosis is characterized by altered microbial composition and abundance across different anatomical sites.
Jie Qiu, Xiaojia Wang, Man Li, Jing Guo, Shipeng Ning, Yi‐Zhou Gao, Xinyi Zhang, Xuli Meng, Yiding Chen, Yunxiang Zhou   +9 more
wiley   +1 more source

An Activity-Based Near-Infrared Glucuronide Trapping Probe for Imaging β-Glucuronidase Expression in Deep Tissues

, 2016
β-glucuronidase is an attractive reporter and prodrug-converting enzyme. The development of near-IR (NIR) probes for imaging of β-glucuronidase activity would be ideal to allow estimation of reporter expression and for personalized glucuronide prodrug ...
Chien-Han Kao (563248), Kuan-Yi Liu (2113501), Steve R. Roffler (75181), Kuo-Hsiang Chuang (600781), Tian-Lu Cheng (563253), I-Hong Harn (2113507), Ta-Chun Cheng (563250), Chih-Hung Chuang (563251), Yu-Cheng Su (1423480), Chien-Shu Chen (771985), Shey-Cherng Tzou (257238), Yu-Ling Leu (2113504)   +11 more
core   +1 more source

Probiotic fermented goat milk incorporated with blackberry (Rubus sp.): A novel functional food product

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND This study created functional fermented goat milk by adding blackberry pulp and probiotics (Lactobacillus acidophilus LA‐5 and Bifidobacterium animalis subsp. lactis Bb‐12). The preparation involved two variations of fermented goat milk with blackberry (Rubus sp.), distinguished by the absence (fermented goat milk, FGM) or inclusion
Bibiana Bittencourt Bicca, Khadija Bezerra Massaut, Elisa dos Santos Pereira, Márcia Vizzotto Foster, Laura Martins Fonseca, Ângela Maria Fiorentini, Graciela Volz Lopes   +6 more
wiley   +1 more source

Physicochemical properties, fermentative profile, microbiological quality, and pathogen contamination of baled silage during long‐term storage

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Baled silage is expanding in Mediterranean regions due to climate change and demand for high‐quality forage; therefore, evaluating the effects of long‐term storage on microbiological and fermentative quality is essential. RESULTS In this study, 115 baled silages were sampled from different farms at 30, 60, 90, 180, and 270 days ...
Lidia Nieddu, Mirko Fresu, Carmelo Mastroeni, Antonio Gallo, Severino Zara, Francesco Fancello, Alberto Stanislao Atzori   +6 more
wiley   +1 more source

Synthesis of Chromen-4-One-Oxadiazole Substituted Analogs as Potent β-Glucuronidase Inhibitors

Molecules, 2019
Chromen-4-one substituted oxadiazole analogs 1–19 have been synthesized, characterized and evaluated for β-glucuronidase inhibition. All analogs exhibited a variable degree of β-glucuronidase inhibitory activity with IC50 values ranging ...
Muhammad Taha, Fazal Rahim, Muhammad Ali, Muhammad Naseem Khan, Mohammed A. Alqahtani, Yasser A. Bamarouf, Mohammed Gollapalli, Rai Khalid Farooq, Syed Adnan Ali Shah, Qamar Uddin Ahmed, Zainul Amiruddin Zakaria   +10 more
doaj   +1 more source

A Doxorubicin-Glucuronide Prodrug Released from Nanogels Activated by High-Intensity Focused Ultrasound Liberated β-Glucuronidase [PDF]

, 2020
The poor pharmacokinetics and selectivity of low-molecular-weight anticancer drugs contribute to the relatively low effectiveness of chemotherapy treatments.
Moonen, Chrit T. W., Pharmaceutics, Metselaar, Josbert M., Moonen, Chrit T.W., Scheeren, Hans W., Besse, Helena C., Hans W. Scheeren, Yinan Chen, Twan Lammers, Deckers, Roel, Scheeren, Hans W, Josbert M. Metselaar, Helena C. Besse, Hennink, Wim E., Metselaar, Josbert M, Roel Deckers, Moonen, Chrit T W, Lammers, Twan, Wim E. Hennink, Besse, Helena C, Hennink, Wim E, Afd Pharmaceutics, Chrit T. W. Moonen, Chen, Yinan   +23 more
core   +1 more source

The effects of the presence of the corneal epithelium and supplemental hydrocortisone on ß-glucuronidase levels with corneal preservation

Clinical Ophthalmology, 2011
Thomas Mauger, Eric QuartettiHavener Eye Institute, Department of Ophthalmology, The Ohio State University, OH, USAPurpose: To analyze the levels of ß-glucuronidase during prolonged (14 day) corneal preservation with epithelialized (EPI) and ...
Mauger TF, Quartetti E
doaj  

Premières observations sur les activités enzymatiques developpées dans le moût de raisins par certains champignons filamenteux

OENO One, 1986
La composition macromoléculaire des extraits alcooliques de moûts parasités par certains champignons filamenteux est variable, également certaines activités enzymatiques qui leur sont associées. Tandis que l'extrait de Botrytis cinerea se caractérise par
Maria Vitória San Romão, Maria Filomena Silva Alemão   +1 more
doaj   +1 more source

Egasyn, a protein complexed with microsomal beta-glucuronidase.

, 1975
Two polypeptide chains are present in murine beta-glucuronidase precipitated with a specific anti-beta-glucuronidase antibody F(ab)2 fragment. One is the catalytic subunit of beta-glucuronidase and the other has the properties predicted for the ...
Tominco, S, Paigen, K, Tomino, S
core  

Indole bearing thiadiazole analogs: synthesis, β-glucuronidase inhibition and molecular docking study

BMC Chemistry, 2019
Background Indole based thiadiazole derivatives (1–22) have synthesized, characterized by NMR and HREI-MS and evaluated for β-Glucuronidase inhibition. All compounds showed outstanding β-glucuronidase activity with IC50 values ranging between 0.5 ± 0.08 ...
Noor Barak Almandil, Muhammad Taha, Mohammed Gollapalli, Fazal Rahim, Mohamed Ibrahim, Ashik Mosaddik, El Hassane Anouar   +6 more
doaj   +1 more source