Results 41 to 50 of about 60,128 (191)

Pregnanediol: its determination and occurrence in the proliferative phase of the normal menstrual cycle [PDF]

, 1960
Thesis (M.D.)--Boston ...
Leventhal, John M.
core  

The estrobolome: Estrogen‐metabolizing pathways of the gut microbiome and their relation to breast cancer

International Journal of Cancer, EarlyView.
Abstract Increasing evidence links the gut microbiome to carcinogenesis. Disruptions in estrogen regulation by the estrobolome—gut microbiota with estrogen‐related functions—may promote breast cancer. However, precise information on estrobolome targets and their underlying mechanisms is limited. This review identifies relevant targets for measuring the
Ashley H. Larnder, Amee R. Manges, Rachel A. Murphy   +2 more
wiley   +1 more source

Plant Hormones Differentially Control the Sub-Cellular Localization of Plasma Membrane Microdomains during the Early Stage of Soybean Nodulation [PDF]

, 2019
Phytohormones regulate the mutualistic symbiotic interaction between legumes and rhizobia, nitrogen-fixing soil bacteria, notably by controlling the formation of the infection thread in the root hair (RH).
Libault, Marc, Qiao, Zhenzhen, Zogli, Prince   +2 more
core   +1 more source

A Novel Series of Synthetic Heparin‐Mimetics–Itaconic Acid‐Containing Copolymers for Targeting Tumor Cell Coagulability and Metastasis

Macromolecular Bioscience, EarlyView.
Heparin is postulated to possess antitumor properties‐ beyond its anticoagulative activities in oncology, but disclosure of targeted activities is complicated by heparins structural variabilities as natural glycosaminoglycans. Here, synthetic noncarbohydrate polymers are presented with tuneable structures as heparin mimetics in in‐vitro‐approaches for ...
Katrin Nekipelov, Abdullah Al Nahain, Sven Otto, Yongbin Xu, Jin‐Ping Li, Natasha Letunica, Simon Collett, Chantal Attard, Paul Monagle, George Vamvounis, John Tsanaktsidis, Vito Ferro, Gerd Bendas   +12 more
wiley   +1 more source

Heterogeneity of Intratumoral Microbiota Within the Tumor Microenvironment and Relationship to Tumor Development

Med Research, EarlyView.
Mutual shaping of tumor microbiota and TME. Intratumoral microbiota—comprising diverse bacteria, fungi, viruses, and intracellular organisms—play critical and dynamic roles in shaping the tumor microenvironment (TME). Their spatial and compositional diversity contributes to both intratumoral and intertumoral heterogeneity, influencing immune modulation
Zhifei Gao, Aimin Jiang, Zizhuo Li, Lingxuan Zhu, Weiming Mou, Weitao Shen, Peng Luo, Bufu Tang, Jian Zhang, Anqi Lin   +9 more
wiley   +1 more source

Stable gene transformation in cowpea (Vigna unguiculata L. Walp.) using particle gun method [PDF]

, 2003
We investigated the possibility of transforming and obtaining transgenic cowpea (Vigna unguiculata L Walp) plants using the particle bombardment process.
Ikea, J, Ingelbrecht, Ivan, Thottappilly, G, Uwaifo, A   +3 more
core   +2 more sources

The C11orf24 Gene as a Useful Biomarker for Predicting Severe Neutropenia in Modified FOLFIRINOX for Pancreatic Cancer

Cancer Science, EarlyView.
FOLFIRINOX improves the prognosis of patients with pancreatic cancer; however, despite UGT1A1 screening, adverse events, such as severe neutropenia, occur frequently. The diagnostic performance of the neutropenia prediction model showed areas under the curve of 0.754 (sensitivity=0.605, specificity=0.848) and 0.856 (sensitivity=0.800, specificity=0.893)
Gen Kanesada, Ryouichi Tsunedomi, Yuki Nakagami, Hiroto Matsui, Yoshitaro Shindo, Shinobu Tomochika, Hirofumi Akita, Tatsuya Ioka, Hidenori Takahashi, Hiroaki Nagano   +9 more
wiley   +1 more source

Structurally-related (−)-epicatechin metabolites in humans: assessment using de novo chemically synthesized authentic standards [PDF]

, 2012
Accumulating data suggest that diets rich in flavanols and procyanidins are beneficial for human health. In this context, there has been a great interest in elucidating the systemic levels and metabolic profiles at which these compounds occur in humans ...
Arts, Auger, Baba, Baba, Balzer, Bors, Carl L. Keen, Donovan, Donovan, Flammer, Grassi, Gunter K. Kuhnle, Hagen Schroeter, Harada, Heiss, Heiss, Heiss, Heiss, Hollenberg, Holt, Javier I. Ottaviani, Koster, Kuhnle, Loke, Mannisto, McCullough, Mink, Mullen, Mursu, Natsume, Neveu, Okushio, Ottaviani, Piskula, Robbins, Roura, Schroeter, Schroeter, Spencer, Stalmach, Taubert, Tony Y. Momma, Unno, Vaidyanathan, Weitering, Zimmermann   +45 more
core   +1 more source

Cardioprotective effects of the extracellular chaperone clusterin in acute myocardial infarction

European Journal of Clinical Investigation, EarlyView.
In vivo, CLU−/− mice were more susceptible to acute myocardial infarction than CLU+/+ mice. Moreover, inflammation and histone levels were significantly increased in CLU−/− mice compared to CLU+/+ mice following ischemia/reperfusion. In vitro, CLU protects cardiomyocytes from histone‐ and/or hypoxia‐induced cell death.
Louwana Allawa, Antoine Poirier, Pascale Pignon, Justine Beaumont, Lucie Lebeau, Agnès Barbelivien, Thomas Bochaton, Céline Beauvillain, Daniel Henrion, Yves Delneste, Pascale Jeannin, Fabrice Prunier, Sophie Tamareille   +12 more
wiley   +1 more source

Calcium/sodium exchange in purified secretory vesicles from bovine neurohypophyses [PDF]

, 1983
Purified secretory vesicles isolated from bovine neurohypophyses take up Na+ under the same circumstances where an efflux of Ca2+ takes place, suggesting a Na+/Ca2+ exchange. Potassium cannot substitute for Na+ in this process. Also, a Ca2+/Ca2+ exchange
Baker, Bers, Blaustein, Blitz, Borle, Brownstein, Böhlen, Conigrave, Gianetto, Gratzl, Gratzl, Johnson, Krieger-Brauer, Krieger-Brauer, Lever, Njus, Normann, Price, Rasmussen, Russell, Russell, Scherman, Scherman, Sillen, Suchard, Særmark, Særmark, Særmark, Thorn, Torp-Pedersen, Torp-Pedersen, van der Meulen, Vilhardt   +32 more
core   +1 more source