Results 61 to 70 of about 31,424 (230)

STREPTOCOCCAL β-GLUCURONIDASE [PDF]

Journal of Bacteriology, 1953
Ralph F. Jacox, Gloria L. Cushing
openaire   +2 more sources

Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis

Immunology, EarlyView.
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay, Mariem Garci, Ahmed Baligh Laaribi, Nabil Mathlouthi, Imene Ouzari   +4 more
wiley   +1 more source

lincRNA6679 promotes FnPR1B expression via phosphorylation‐activated FnWRKY14 to enhance strawberry resistance to Botrytis cinerea

Journal of Integrative Plant Biology, EarlyView.
In strawberry, Botrytis cinerea induces the expression of the long, intergenic non‐coding RNA lincRNA667，which upregulates the transcription factor gene FnWRKY14. FnWRKY14 then binds to the promoter of the pathogenesis‐related gene FnPR1B, enhancing strawberry resistance to B. cinerea.
Yuhan Guan, Zhuo Zhang, Zihui Zhang, Yan Wang, Wei Guo, Zhihong Zhang, He Li   +6 more
wiley   +1 more source

The effects of the presence of the corneal epithelium and supplemental hydrocortisone on ß-glucuronidase levels with corneal preservation

Clinical Ophthalmology, 2011
Thomas Mauger, Eric QuartettiHavener Eye Institute, Department of Ophthalmology, The Ohio State University, OH, USAPurpose: To analyze the levels of ß-glucuronidase during prolonged (14 day) corneal preservation with epithelialized (EPI) and ...
Mauger TF, Quartetti E
doaj  

Indole bearing thiadiazole analogs: synthesis, β-glucuronidase inhibition and molecular docking study

BMC Chemistry, 2019
Background Indole based thiadiazole derivatives (1–22) have synthesized, characterized by NMR and HREI-MS and evaluated for β-Glucuronidase inhibition. All compounds showed outstanding β-glucuronidase activity with IC50 values ranging between 0.5 ± 0.08 ...
Noor Barak Almandil, Muhammad Taha, Mohammed Gollapalli, Fazal Rahim, Mohamed Ibrahim, Ashik Mosaddik, El Hassane Anouar   +6 more
doaj   +1 more source

In Silico Structural Analysis of Human β-Glucuronidase for Antibody-Drug Conjugates Optimization. [PDF]

Proteins
ABSTRACT Human β‐glucuronidase (HGUSB), a key lysosomal glycosyl hydrolase for the degradation pathway of glycosaminoglycans (GAGs), plays a crucial role in cell proliferation and inflammation, making it a promising target for novel therapeutic strategies including antibody‐drug conjugates (ADCs) with β‐glucuronic linkers.
Canini G, Saporiti S, Coppa C, Rossi M, Centola F, Arcovito A.   +5 more
europepmc   +2 more sources

OsCPN10a, cooperating with OsCPN20 and OsHSP60‐3B negatively regulate ABA signaling and enhance seed storability in rice

Journal of Integrative Plant Biology, EarlyView.
Abscisic acid signaling homeostasis is essential for seed storability. The molecular chaperone OsCPN10a enhances rice seed storability by forming a trimeric chaperone complex with OsCPN20‐OsHSP60‐3B that attenuates abscisic acid signaling via direct interaction with OsPYL10‐OsABIL1, thereby maintaining starch integrity and offering a promising target ...
Sufeng Liao, Yidong Wei, Yongsheng Zhu, Kunyang Li, Ting Chen, Shuai Zhao, Fangxi Wu, Jinlan Wang, Pengbo Yu, Hongguang Xie, Liping Chen, Qiuhua Cai, Huaan Xie, Jianfu Zhang   +13 more
wiley   +1 more source

The Arabidopsis NPF7.2 mediates coumarin uptake for root iron acquisition

New Phytologist, EarlyView.
Summary Iron (Fe) is a transition metal necessary for achieving essential physiological processes throughout the plant lifecycle. In Arabidopsis thaliana, secreting Fe‐mobilizing coumarins (FMC) is a key mechanism enabling roots to acquire nonbioavailable Fe present in soils.
Shunsuke Watanabe, Meijie Li, Alice Rossille, Chérhazad Boustani, Kevin Robe, Yuri Kanno, Mitsunori Seo, Christian Dubos   +7 more
wiley   +1 more source

Inhibitory Effects of Baicalein Derived from Japanese Traditional Herbal Medicine on SN-38 Glucuronidation

Journal of Pharmacy & Pharmaceutical Sciences, 2018
Purpose: The chemotherapeutic agent irinotecan is hydrolyzed to its active form SN-38 by human carboxyesterases, but SN-38 is converted into the inactive form SN-38G by hepatic UDP-glucuronosyltransferases (UGTs).
Takashi Satoh, Ayaka Igarashi, Misaki Tanno, Koki Yamada, Natsuko Takahashi-Suzuki, Kazuhiro Watanabe   +5 more
doaj   +1 more source

Cell cycle follows ‘pause and play’ mechanism in salt and cold stress recovery in diverse plant species

New Phytologist, EarlyView.
Summary Changes to organismal growth induced by environmental stress are orchestrated at the cellular level. These periods of stress may be followed by recovery periods, when plants have the opportunity to return to normal growth conditions. However, the cell cycle mechanisms underlying recovery are poorly understood.
Olivia S. Hazelwood, Kamryn A. Diehl, Vicky Hollenbeck, Joh Demura‐Devore, Dustin Herb, Joseph P. Gallagher, M. Arif Ashraf   +6 more
wiley   +1 more source