Results 141 to 150 of about 14,230 (233)

UGTformer: a pretrained graph transformer model for predicting UDP-glucuronosyltransferase-mediated drug metabolism. [PDF]

J Cheminform
Zhan M, Li X, Xiong L, Song W, Fang J, Liu G, Tang Y, Li W.   +7 more
europepmc   +1 more source

Survival of patients with colorectal or pancreatic cancer who received <i>UGT1A1</i> genotype-guided dosing of irinotecan in the Netherlands (2017-2024): a retrospective, multicentre cohort study. [PDF]

Lancet Reg Health Eur
Peeters SLJ, Heersche N, Böhm D, Böhringer S, Guiljam R, Hulshof EC, de Man FM, de With M, Joosse M, Oomens G, Wu QY, Osman A, Bins S, van Hellemond IEG, Haberkorn BCM, Verschoor AJ, Wumkes ML, van Schaik RHN, Thijs AM, Gelderblom H, Guchelaar HJ, Mathijssen RHJ, Deenen MJ.   +22 more
europepmc   +1 more source

Overlooked aspects of scaling enzyme activity through abundance across tissues and individuals: Insights from k_cat measurements in matched liver and intestinal samples. [PDF]

Drug Metab Dispos
Al-Majdoub ZM, Barber J, Rostami-Hodjegan A, Galetin A, Scotcher D.   +4 more
europepmc   +1 more source

Dexamethasone-Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH-7 Cells. [PDF]

Fundam Clin Pharmacol
Yu H, Lee SH, Kim JH, Kim SJ, Kang HE.
europepmc   +1 more source

From Childhood Icterus to Adolescent Gallstones: Clinically Diagnosed Crigler-Najjar Syndrome Type II. [PDF]

Clin Case Rep
Goswami DK, Goswami B, Shaikh S, Rahimoon AG, Soni R, Kamil KA.   +5 more
europepmc   +1 more source

Neoadjuvant chemoradiotherapy with capecitabine and irinotecan guided by UGT1A1 status in patients with locally advanced rectal cancer: 5-year update of the CinClare trial. [PDF]

Cancer Commun (Lond)
Zhang Z, Sun X, Liu A, Zhu Y, Zhang T, Liu L, Jia J, Tan S, Wu J, Wang X, Zhou J, Yang J, Zhang C, Zhang H, He X, Cai G, Huang C, Xia F, Wan J, Zhang H, Shen L, Wang L, Zhang W, Cai S, Zhu J.   +24 more
europepmc   +1 more source

First use of nitazoxanide in Kelleni's protocol for managing severe bronchiolitis in a 9-month-old infant: A case report and review of literature. [PDF]

World J Clin Cases
Kelleni MT.
europepmc   +1 more source

Apalutamide-Induced Hypothyroidism Associated With Increased Thyroid Hormone Clearance in Metastatic Prostate Cancer Patient: A Case Report. [PDF]

IJU Case Rep
Furumido J, Yamashita A, Kato R, Hori K.
europepmc   +1 more source

In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug-Metabolizing Enzymes. [PDF]

J Clin Pharmacol
Zhou XJ, Vo A, Morelli G, Montrond M, Lynch S, Pietropaolo K, Belanger B, Good S, Horga A, Agrawal N, Hammond J.   +10 more
europepmc   +1 more source

The involvement of miRNAs in CYP450 enzymes and UDP-glucuronosyltransferases regulation in the human liver. [PDF]

Sci Rep
Szeląg-Pieniek S, Perużyńska M, Komaniecka N, Kurzawski M, Oswald S, Łapczuk-Romańska J, Droździk M.   +6 more
europepmc   +1 more source