Results 121 to 130 of about 14,230 (233)

Drug-Metabolizing Gene Expression Identity: Comparison Across Liver Tissues and Model Cell Lines. [PDF]

Biomedicines
Arzumanian VA, Timofeeva EV, Kiseleva OI, Poverennaya EV.   +3 more
europepmc   +1 more source

Liver Transplantation Outcomes in Crigler-Najjar Syndrome in Iran: A Single-Center Retrospective Cohort Study Over 20 Years. [PDF]

Health Sci Rep
Teimoury S, Beyzaei Z, Shamsaeefar A, Kazemi K, Nikeghbalian S, Malekhosseini SA, Geramizadeh B.   +6 more
europepmc   +1 more source

Evolutionary diversity of sphingolipid metabolism proteins in fungi. [PDF]

IMA Fungus
Płecha M, Sokołowska B, Barua D, Bartczak J, Sobczyk M, Koperska D, Kułakowska A, Komosa A, Muszewska A.   +8 more
europepmc   +1 more source

Development and characterization of near-isogenic lines for quantitative trait locus qDT.3B.1 underlying drought tolerance in wheat. [PDF]

Plant Genome
Caguiat JD, Mia MS, Liu H, Yan G, Siddique KHM.   +4 more
europepmc   +1 more source

Modulation of Macrophage Inflammatory Responses by UDP-Glucuronosyltransferase-Mediated PGE₂ Glucuronidation. [PDF]

J Pers Med
Lee D, Cho HY, Ahn S, Cho YS, Kim DH, Shin JG, Lee SJ.   +6 more
europepmc   +1 more source

ALTERED UDP-GLUCURONOSYLTRANSFERASE EXPRESSION IN NONALCOHOLIC STEATOHEPATITIS AND IMPLICATIONS FOR DRUG METABOLISM

, 2018
Nonalcoholic steatohepatitis (NASH) affects the regulation of drug metabolizing enzymes and transporters, which leads to a variability in the disposition of drugs for individuals.
Carroll, Kim Young
core  

Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids

, 2009
Tetrahydrocannabinol (9-THC), the primary psychoactive ingredi-ent in marijuana, is subject to cytochrome P450 oxidation and subsequent UDP-glucuronosyltransferase (UGT)-dependent gluc-uronidation.
Cheryl F. Lichti, Anna Gallus-zawada, Anna Mazur, Agnieszka K. Zielinska, Stacie M. Bratton, Paul L. Prather, Moshe Finel, Jeffery H. Moran, Grover P. Miller   +8 more
core  

Between Crigler-Najjar Syndrome Type II and Gilbert Syndrome: Expanding the Spectrum of Uridine Diphosphate Glucuronosyltransferase 1A1 (UGT1A1)-Related Hyperbilirubinemia. [PDF]

Cureus
Jesus Sá C, Vilar Queirós R, Pessoa T, Santos S, Castilho S.   +4 more
europepmc   +1 more source

Ecopipam, a Dopamine D1 Receptor Antagonist: Pharmacokinetics, Mass Balance, and Metabolism in Healthy Volunteers. [PDF]

Clin Transl Sci
Schmith VD, English S, Dymond A, Holdsworth C, Stow R, Holbrook E, Schleyer J, Wanaski SP.   +7 more
europepmc   +1 more source

Analysis of UGT1A1 germline variants in patients with advanced breast cancer treated with trastuzumab-deruxtecan: results from the PROCURE Project. [PDF]

ESMO Open
Sánchez-Bayona R, de Nicolás-Hernández J, Saura C, Gion M, Cejalvo JM, Llabrés E, Cortés J, Falcón A, Pernas S, López de Sa A, Vidal M, Hinojo C, Curiel T, Cruz J, Martínez V, Cantos B, Echarri MJ, Gallegos I, Bueno C, Vargas AM, Escrivá-de-Romaní S, Fullana B, Cobos MA, Arenas A, Joval-Ramentol L, Ortiz P, Pascual T, Valdivia C, Villacampa G, Ciruelos E, Rodriguez-Antona C.   +30 more
europepmc   +1 more source