Results 111 to 120 of about 22,737 (234)

ケイカチュウ ニ イッカセイ コウビリルビン ケッショウ オ テイシタ ネフローゼ ショウコウグン ノ 2レイ [PDF]

, 2004
We present two patients with idiopathic nephrotic syndrome who showed temporary indirect hyperbilirubinemia during the course of treatment with immunosuppressant drugs and/or steroids.
Liang Lijun
core   +1 more source

The Survival and Physiological Response of Calliptamus abbreviatus Ikonn (Orthoptera: Acrididae) to Flavonoids Rutin and Quercetin

Insects
Insect-resistant substances from plants are important natural resources that human beings can potentially develop and use to control pests. In this study, we explored the adverse effects of rutin and quercetin on grasshopper (Calliptamus abbreviatus), as
Xunbing Huang, Li Zheng, Yueyue Wang
doaj   +1 more source

Applied physiologically‐based pharmacokinetic modeling to assess uridine diphosphate‐glucuronosyltransferase‐mediated drug–drug interactions for Vericiguat

CPT: Pharmacometrics & Systems Pharmacology
Vericiguat (Verquvo; US: Merck, other countries: Bayer) is a novel drug for the treatment of chronic heart failure. Preclinical studies have demonstrated that the primary route of metabolism for vericiguat is glucuronidation, mainly catalyzed by uridine ...
Sebastian Frechen, Ibrahim Ince, André Dallmann, Michael Gerisch, Natalia A. Jungmann, Corina Becker, Maximilian Lobmeyer, Maria E. Trujillo, Shiyao Xu, Rolf Burghaus, Michaela Meyer   +10 more
doaj   +1 more source

Tapentadol withdrawal, a newer trend in opioid overuse in Nepal: A case report

Journal of Nepal Health Research Council
Crigler–Najjar Syndrome Type 2 (CNS2) is a rare autosomal recessive disorder characterized by unconjugated hyperbilirubinemia due to partial deficiency of the enzyme uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1).
Hemant Chand, Om Prakash Bhatta, Sabita Chand, Neha Dangol, Sachin Awasthi, Ram Chandra Poudel, Ram Prasad Lamichhane   +6 more
doaj   +1 more source

A Comparative Analysis of Michaelis-Menten, Hill, and Allosteric Models in Drug Metabolism

Iraqi Journal of Industrial Research
Background: Enzyme Kinetics it is a fundamental part of metabolic biochemistry because it helps to explore the mechanism of action and interaction of all substrates under the influence as well as environmental factors.
Ziyad K. Radeef
doaj   +1 more source

Pharmacogenetics of uridine diphosphate glucuronosyltransferase (UGT2B7) genetic polymorphism on valproic acid pharmacokinetics in epilepsy [PDF]

, 2014
Gauthaman Karunakaran, Manjari M Tripathi, Mubarak Al-Gahtany, Murali Munisamy, Vivekanandhan Subbiah   +4 more
core   +1 more source

Drug-Metabolizing Gene Expression Identity: Comparison Across Liver Tissues and Model Cell Lines. [PDF]

Biomedicines
Arzumanian VA, Timofeeva EV, Kiseleva OI, Poverennaya EV.   +3 more
europepmc   +1 more source

UDP-Glucuronosyltransferase 2B17 [PDF]

, 2020
openaire   +1 more source

Modulation of Macrophage Inflammatory Responses by UDP-Glucuronosyltransferase-Mediated PGE₂ Glucuronidation. [PDF]

J Pers Med
Lee D, Cho HY, Ahn S, Cho YS, Kim DH, Shin JG, Lee SJ.   +6 more
europepmc   +1 more source

Between Crigler-Najjar Syndrome Type II and Gilbert Syndrome: Expanding the Spectrum of Uridine Diphosphate Glucuronosyltransferase 1A1 (UGT1A1)-Related Hyperbilirubinemia. [PDF]

Cureus
Jesus Sá C, Vilar Queirós R, Pessoa T, Santos S, Castilho S.   +4 more
europepmc   +1 more source