Results 211 to 220 of about 25,858 (256)

Prediction of UGT-mediated phase II metabolism via ligand- and structure-based predictive models. [PDF]

open access: yesJ Cheminform
Bono L   +8 more
europepmc   +1 more source

OATP2B1 Deficiency Ameliorates Irinotecan-Induced Gastrointestinal Toxicity. [PDF]

open access: yesClin Transl Sci
Taheri H   +8 more
europepmc   +1 more source

Monogenic Contributions to Familial Endometriosis: A Scoping Review.

open access: yesGynecol Obstet Invest
Joshy LE   +7 more
europepmc   +1 more source
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UDP-Glucuronosyltransferases

Current Drug Metabolism, 2000
Glucuronidation represents a major pathway which enhances the elimination of many lipophilic xenobiotics and endobiotics to more water-soluble compounds. The UDP-glucuronosyltransferase (UGT) family catalyzes the glucuronidation of the glycosyl group of a nucleotide sugar to an acceptor compound (aglycone) at a nucleophilic functional group of oxygen ...
C D, King   +3 more
openaire   +2 more sources

Steroid UDP glucuronosyltransferases

The Journal of Steroid Biochemistry and Molecular Biology, 1992
The glucuronidation of steroids is a major process necessary for their elimination in the bile and urine. In general, steroid glucuronides are biologically less reactive than their parent steroids. However, in some cases often associated with disease and steroid therapy, more reactive or toxic glucuronides may be formed.
P I, Mackenzie, L, Rodbourne, S, Stranks
openaire   +2 more sources

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