Results 161 to 170 of about 7,531 (182)

Trans-Zeatin Enhances <i>Auxenochlorella pyrenoidosa</i> Growth by Coordinating Carbon-Nitrogen Metabolism and Antioxidant Defense. [PDF]

Microorganisms
Ma YL, Li M, Lei Q, Ma HJ, An YJ.
europepmc   +1 more source

Prion diseases disrupt glutamate/glutamine metabolism in skeletal muscle. [PDF]

PLoS Pathog
Caredio D, Koderman M, Frontzek KJ, Sorce S, Nuvolone M, Bremer J, Mariutti G, Schwarz P, Madrigal L, Mitrovic M, Sellitto S, Streichenberger N, Scheckel C, Aguzzi A.   +13 more
europepmc   +1 more source

A method for the detection and enrichment of endogenous cereblon substrates

Lloyd HC, Li Y, Connor Payne N, Zhao Z, Xu W, Kroupova A, Zollman D, Long T, Kabir F, Chen M, Freeman R, Feng EY, Xi S, Hsu Y, Ciulli A, Mazitschek R, Woo CM.   +16 more
europepmc   +1 more source

METTL16 emerges as a pivotal epitranscriptomic regulator, linking RNA modification, tumor progression, and immune modulation. [PDF]

Front Immunol
Wang Q, Jiang X, Yuan Y, Li C.
europepmc   +1 more source

TERT silencing alters the expression of ARG1, GLUL, VIM, NES genes and hsa-miR-29b-3p in the T98G cell line

Nucleosides, Nucleotides & Nucleic Acids, 2022
The central function of telomerase is maintaining the telomere length. However, several extra-telomeric roles have been identified for this protein complex.
Yeimy González‐Giraldo, Angela Garcia, Andrés Felipe Aristizábal-Pachón   +2 more
semanticscholar   +4 more sources

НАПРАВЛЕННАЯ ИНАКТИВАЦИЯ ГЕНОВ dhfr, glul, bak1, bax МЕТОДОМ МУЛЬТИПЛЕКСНОГО ГЕНОМНОГО РЕДАКТИРОВАНИЯ КЛЕТОК CHO

Доклады Российской академии наук. Науки о жизни, 2022
Н. А. Орлова, Л. К. Даянова, Е. А. Гаямова, Maria V. Sinegubova, С. В. Ковнир, И. И. Воробьев   +5 more
semanticscholar   +3 more sources

Targeted Knockout of the dhfr, glul, bak1, and bax Genes by the Multiplex Genome Editing in CHO Cells

Doklady Biochemistry and Biophysics, 2022
The Chinese hamster ovary cell line CHO is widely used for biopharmaceutical production. Genome editing makes it possible to improve the growth properties of cells, their auxotrophy, and the functioning of the apoptosis and autophagy induction systems.
N. A. Orlova, L. K. Dayanova, E. A. Gayamova, M. V. Sinegubova, S. V. Kovnir, I. I. Vorobiev   +5 more
semanticscholar   +4 more sources

GLUL Promotes Cell Proliferation in Breast Cancer

Journal of cellular biochemistry, 2017
Glutamate-ammonia ligase (GLUL) belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. Here, we found higher expression of GLUL in the breast cancer patients was associated with larger tumor size and higher level of HER2 expression.
Yanyan Wang, Shao‐Hua Fan, Jun Lü, Zifeng Zhang, Dongmei Wu, Zhiyong Wu, Yuan‐Lin Zheng   +6 more
semanticscholar   +5 more sources

Abstract 2466: Stochastic loss of GLUL expression correlates with STK11-loss-dependent glutamine addiction and may impact anti-PD1 therapy resistance in NSCLC

Cancer Research, 2021
Abstract Our work aims to delineate the molecular interactions linking somatic disruption of Serine-Threonine Kinase 11 (STK11) with anti-PD1 therapy resistance in KRAS-driven lung adenocarcinoma (LUAD). Data presented here suggests glutamine synthetase (GLUL) may modulate this phenotype.
Sean Lenahan, Hailey Sarausky, David J. Seward   +2 more
semanticscholar   +3 more sources