Results 171 to 180 of about 7,531 (182)

Assignment of the porcine GLUL gene to the distal end of chromosome 9q

open access: closedAnimal Genetics, 2002
A. Stratil   +7 more
semanticscholar   +4 more sources

Circ_0006949 as a potential non-invasive diagnosis biomarker promotes the proliferation of NSCLC cells via miR-4673/GLUL axis

open access: closedBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
The 5-year survival for non-small cell lung cancer (NSCLC) remains
Changsen Bai   +15 more
semanticscholar   +4 more sources

Association analysis of the glutamic acid decarboxylase 2 and the glutamine synthetase genes (GAD2, GLUL) with schizophrenia

open access: closedPsychiatric Genetics, 2008
As dysfunction of glutamatergic neurotransmission is one of the plausible hypotheses for the pathogenesis of schizophrenia, genes involved in the glutamate neurotransmitter system are candidates for schizophrenia susceptibility. The aim of this study is to clarify the contribution of two genes encoding glutamate metabolic enzymes: the glutamic acid ...
Shinsaku Arai   +6 more
semanticscholar   +4 more sources

Abstract P4-06-10: Epigenetic silencing of glutamine synthetase (Glul) defines glutamine depletion therapy

open access: closedCancer Research, 2012
Abstract Background: Methylation-dependent transcriptional silencing of genes involved in amino acid synthesis can provide potential targets for novel synthetic lethality strategies. Glutamine synthetase (Glul) is the key enzyme in the biosynthesis of glutamine.
F. Cavicchioli   +8 more
semanticscholar   +3 more sources

SIRT6–GLUL axis: rewiring nitrogen metabolism in intrahepatic cholangiocarcinoma

open access: closedGut
Intrahepatic cholangiocarcinoma ...
Huiping Zhou   +3 more
openalex   +2 more sources

In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer’s Disease, Major Depressive Disorder, and Type 2 Diabetes

open access: closedJournal of Molecular Neuroscience, 2018
Ammonia is a toxic by-product of protein catabolism and is involved in changes in glutamate metabolism. Therefore, ammonia metabolism genes may link a range of diseases involving glutamate signaling such as Alzheimer's disease (AD), major depressive disorder (MDD), and type 2 diabetes (T2D).
Jeddidiah W. D. Griffin   +3 more
semanticscholar   +5 more sources

In-111-DTPA-D-Glul-minigastrin versus In-111-pentetreotide for the detection of neuroendocrine gastroenteropancreatic (GEP) tumors

open access: closedGastroenterology, 2003
M. Wied   +8 more
semanticscholar   +3 more sources
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Glutamine synthetase activity and the expression of three glul paralogues in zebrafish during transport.

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2012
The enzyme glutamine synthetase (GS; glutamate-ammonia ligase, EC 6.3.1.2) plays an important role in the nitrogen metabolism of fish. In this study the GS activity and the corresponding genes were examined to understand how they are regulated in zebrafish in response to hyperammonemic stress during a 72 h simulated transport. Whole body ammonia levels,
A. Dhanasiri, J. Fernandes, V. Kiron
semanticscholar   +3 more sources

Chromosomal mapping of a family of human glutamine synthetase genes: functional gene (GLUL) on 1q25, pseudogene (GLULP) on 9p13, and three related genes (GLULL1, GLULL2, GLULL3) on 5q33, 11p15, and 11q24.

open access: yesGenomics, 1996
Glutamine synthetase (GS) is a ubiquitous enzyme that catalyzes the ATP-dependent conversion of glutamate to glutamine using ammonia as the nitrogen source. Using human GS cDNA as a probe, a bacterial artificial chromosome (BAC) library consisting of two-fold coverage of the human genome was screened, and 18 clones were obtained.
Yimin Wang   +5 more
semanticscholar   +3 more sources

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