Results 171 to 180 of about 7,531 (182)
The bovine glutamine synthase gene ( GLUL ) maps to 10q33 and a pseudogene ( GLULP ) to 16q21
Julio Masabanda +4 more
semanticscholar +4 more sources
Assignment of the porcine GLUL gene to the distal end of chromosome 9q
A. Stratil +7 more
semanticscholar +4 more sources
The 5-year survival for non-small cell lung cancer (NSCLC) remains
Changsen Bai +15 more
semanticscholar +4 more sources
As dysfunction of glutamatergic neurotransmission is one of the plausible hypotheses for the pathogenesis of schizophrenia, genes involved in the glutamate neurotransmitter system are candidates for schizophrenia susceptibility. The aim of this study is to clarify the contribution of two genes encoding glutamate metabolic enzymes: the glutamic acid ...
Shinsaku Arai +6 more
semanticscholar +4 more sources
Abstract Background: Methylation-dependent transcriptional silencing of genes involved in amino acid synthesis can provide potential targets for novel synthetic lethality strategies. Glutamine synthetase (Glul) is the key enzyme in the biosynthesis of glutamine.
F. Cavicchioli +8 more
semanticscholar +3 more sources
SIRT6–GLUL axis: rewiring nitrogen metabolism in intrahepatic cholangiocarcinoma
Intrahepatic cholangiocarcinoma ...
Huiping Zhou +3 more
openalex +2 more sources
Ammonia is a toxic by-product of protein catabolism and is involved in changes in glutamate metabolism. Therefore, ammonia metabolism genes may link a range of diseases involving glutamate signaling such as Alzheimer's disease (AD), major depressive disorder (MDD), and type 2 diabetes (T2D).
Jeddidiah W. D. Griffin +3 more
semanticscholar +5 more sources
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Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2012
The enzyme glutamine synthetase (GS; glutamate-ammonia ligase, EC 6.3.1.2) plays an important role in the nitrogen metabolism of fish. In this study the GS activity and the corresponding genes were examined to understand how they are regulated in zebrafish in response to hyperammonemic stress during a 72 h simulated transport. Whole body ammonia levels,
A. Dhanasiri, J. Fernandes, V. Kiron
semanticscholar +3 more sources
The enzyme glutamine synthetase (GS; glutamate-ammonia ligase, EC 6.3.1.2) plays an important role in the nitrogen metabolism of fish. In this study the GS activity and the corresponding genes were examined to understand how they are regulated in zebrafish in response to hyperammonemic stress during a 72 h simulated transport. Whole body ammonia levels,
A. Dhanasiri, J. Fernandes, V. Kiron
semanticscholar +3 more sources
Glutamine synthetase (GS) is a ubiquitous enzyme that catalyzes the ATP-dependent conversion of glutamate to glutamine using ammonia as the nitrogen source. Using human GS cDNA as a probe, a bacterial artificial chromosome (BAC) library consisting of two-fold coverage of the human genome was screened, and 18 clones were obtained.
Yimin Wang +5 more
semanticscholar +3 more sources

