SE(3)-Equivariant Ternary Complex Prediction Towards Target Protein Degradation [PDF]
Targeted protein degradation (TPD) induced by small molecules has emerged as a rapidly evolving modality in drug discovery, targeting proteins traditionally considered "undruggable". Proteolysis-targeting chimeras (PROTACs) and molecular glue degraders (MGDs) are the primary small molecules that induce TPD.
arxiv
Differential Cell Death Pathways Induced by Oxidative Stress in Multi-Organs of Amur Grayling (<i>Thymallus grubii</i>) Under Gradient Ammonia Stress. [PDF]
Zhai C, Li Y, Wang R, Zhang Y, Ma B.
europepmc +1 more source
Insights into the Antimicrobial Mechanisms of a Scorpion Defensin on <i>Staphylococcus aureus</i> Using Transcriptomic and Proteomic Analyses. [PDF]
Yang X+8 more
europepmc +1 more source
Targeting amino acid metabolism to inhibit gastric cancer progression and promote anti-tumor immunity: a review. [PDF]
Jiang Y+11 more
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New Targets for an Old Drug: A Chemical Proteomics Approach to Unraveling the Molecular Mechanism of Action of Methotrexate [PDF]
Christopher M. Hosfield+8 more
core +1 more source
Two Novel Bacterial Species, Rhodanobacter lycopersici sp. nov. and Rhodanobacter geophilus sp. nov., Isolated from the Rhizosphere of Solanum lycopersicum with Plant Growth-Promoting Traits. [PDF]
Woo H+6 more
europepmc +1 more source
Glutamine Synthetase: Diverse Regulation and Functions of an Ancient Enzyme. [PDF]
Tecson MCB, Geluz C, Cruz Y, Greene ER.
europepmc +1 more source
Glutamate Supplementation Regulates Nitrogen Metabolism in the Colon and Liver of Weaned Rats Fed a Low-Protein Diet. [PDF]
Jiang D+5 more
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Pyropheophytin a accompanies pheophytin a in darkened light grown cells of Euglena [PDF]
RĂ¼diger, W.+4 more
core
Transcriptomics and proteomics provide insights into the adaptative strategies of Tibetan naked carps (Gymnocypris przewalskii) to saline-alkaline variations. [PDF]
Zhou B+10 more
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