Results 131 to 140 of about 41,570 (221)
Eye and Brain, 2023 Guihua Xu, Juanjuan Wang, Yiting Zhang, Zilin Chen, Ruidong Deng Eye Department, Huizhou Municipal Central Hospital, Huizhou, Guangdong, People’s Republic of ChinaCorrespondence: Ruidong Deng; Zilin Chen, Email 359849662@qq.com; boydongdong1@126 ...
Xu G, Wang J, Zhang Y, Chen Z, Deng R
doaj
Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure [PDF]
, 2015 Hepatocellular carcinoma (HCC) is characterized by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which activates the unfolded protein response (UPR).
Ampe, Christophe +16 more
core +3 more sources
Decoding plant defense signaling using the defenseless mutant
New Phytologist, Volume 250, Issue 2, Page 1141-1156, April 2026.Summary Can plants live without defenses? Mutant analysis in Arabidopsis thaliana has identified numerous regulators of biotic, abiotic, and hormone‐based defenses, but the redundancy among separate defense pathways remains unexplored. We constructed an Arabidopsis mutant, defenseless, lacking six canonical defense pathways using abi1‐1 (abscisic acid),
Bikash Baral, Mikael Brosché
wiley +1 more source
Redox BiologyGlutathione (GSH) is a major endogenous antioxidant, and its depletion has been observed in several brain diseases including epilepsy. Previous studies in our laboratory have shown that dimercaprol (DMP) can elevate GSH via post-translational activation ...
Li-Ping Liang +3 more
doaj +1 more source
Inhibition of Glutathione Synthesis via Decreased Glucose Metabolism in Stored RBCs
Cellular Physiology and Biochemistry, 2018 Background/Aims: Although red blood cells (RBCs) transfusions can be lifesaving, they are not without risk. RBCs storage is associated with the abnormal metabolism of glutathione (GSH), which may increase the risk of the oxidative damage of RBCs after ...
Yanlian Xiong +10 more
doaj +1 more source
Arabidopsis thaliana Glutamate-Cysteine Ligase [PDF]
Journal of Biological Chemistry, 2004 Joseph M. Jez +2 more
openaire +1 more source
Nrf2 activation in the treatment of neurodegenerative diseases:A focus on its role in mitochondrial bioenergetics and function [PDF]
, 2016 The nuclear factor erythroid-derived 2 (NF-E2)-related factor 2 (Nrf2) is a transcription factor well-known for its function in controlling the basal and inducible expression of a variety of antioxidant and detoxifying enzymes.
Abramov, Andrey Y. +2 more
core +2 more sources
New Phytologist, Volume 250, Issue 2, Page 788-798, April 2026.Summary Generation of competent offspring is vital for the prosperity of flowering plants. The pistil not only functions as a conduit for pollen tubes to grow to the ovary but also provides a selective venue for facilitating the growth of compatible pollen tubes and discouraging invaders and incompatible pollen.
Tong Zhang +3 more
wiley +1 more source
Limits of aerobic metabolism in cancer cells [PDF]
, 2017 Cancer cells exhibit high rates of glycolysis and glutaminolysis. Glycolysis can provide energy and glutaminolysis can provide carbon for anaplerosis and reductive carboxylation to citrate.
Fernandez-de-Cossio-Diaz, Jorge +1 more
core +3 more sources
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.Heat shock induces Arc/Arg3.1 Cys34‐Cys159 disulfide crosslinking, promoting oligomerization and Hsp70‐CHIP‐dependent ubiquitination followed by proteasomal degradation during recovery. Disrupting disulfide formation (C159A) impairs CHIP‐mediated ubiquitination and stabilizes Arc/Arg3.1, whereas HSF1 loss limits inducible Hsp70 and leads to Arc ...
Dami So +7 more
wiley +1 more source