Results 161 to 170 of about 41,570 (221)

Coordinated transcriptional regulation between a reactive oxygen species-responsive gene network and the circadian clock in Arabidopsis thaliana : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Plant Biology at Massey University, Plant Biology, New Zealand [PDF]

, 2012
Most organisms have evolved endogenous biological clocks as internal timekeepers to fine-tune physiological processes to the external environment. Energetic cycles such as photosynthesis and glycolytic cycles are physiological processes that have ...
Lai, Alvina Grace
core  

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

Photochemistry and Photobiology, Volume 102, Issue 2, Page 370-399, March/April 2026.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima, Rebeca Barros Nascimento, Ana Paula Mariano Santos Ginez, Maria Stella Moreira, Rebeca Boltes Cecatto, Rodrigo Labat Marcos, Maria Fernanda Setúbal Destro Rodrigues   +6 more
wiley   +1 more source

Amino acid restriction sensitizes lung cancer cells to ferroptosis via GCN2-dependent activation of the integrated stress response

Redox Biology
Lung cancer cells are vulnerable to iron-dependent oxidation of phospholipids leading to ferroptosis, a process countered by glutathione peroxidase-4 that converts lipid hydroperoxides to lipid alcohols using glutathione as reducing agent.
Viktor Antonsson Garellick, Nadia Gul, Parvin Horrieh, Dyar Mustafa, Angana A.H. Patel, Martin Dankis, Samantha W. Alvarez, Johanna Berndtson, Saeed Mahdavi, Maria Schwarz, Andreas Persson, Fikret Zahirovic, Clotilde Wiel, Volkan I. Sayin, Per Lindahl   +14 more
doaj   +1 more source

Glutamate-cysteine ligase deficiency [PDF]

, 2020
openaire   +1 more source

Down regulation of glutathione and glutamate cysteine ligase in the inflammatory response of macrophages. [PDF]

Free Radic Biol Med, 2020
Zhang H, Zhang SJ, Lyn N, Florentino A, Li A, Davies KJA, Forman HJ.   +6 more
europepmc   +1 more source

Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress. [PDF]

Front Mol Biosci, 2020
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y.   +11 more
europepmc   +1 more source

Post-translational regulation and evolution of plant gamma-glutamate cysteine ligase

, 2007
Glutamate cysteine ligase (GCL) is catalyzing the rate-limiting step in glutathione (GSH) synthesis. A complex regulation of this enzyme is required to integrate various signals as GSH is fulfilling a plethora of functions in housekeeping metabolism, stress defence, and in the regulation of development.
openaire   +2 more sources

A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato. [PDF]

Adv Sci (Weinh)
Tian X, Li M, Huang X, Wirtz M, Zheng X, Fan S, Tian J, Liu S, Liu Z, Zhao H.   +9 more
europepmc   +1 more source

Glutamate-cysteine ligase as a diagnostic biomarker and therapeutic target in Parkinson's disease: a multi-omics and experimental study. [PDF]

Eur J Med Res
Li X, Wang M, Zhong C, Xia J, Tian L, Wang J, Yang D.   +6 more
europepmc   +1 more source