Results 161 to 170 of about 41,955 (229)

Glutamate-cysteine ligase deficiency [PDF]

, 2020
openaire   +1 more source

Down regulation of glutathione and glutamate cysteine ligase in the inflammatory response of macrophages. [PDF]

Free Radic Biol Med, 2020
Zhang H, Zhang SJ, Lyn N, Florentino A, Li A, Davies KJA, Forman HJ.   +6 more
europepmc   +1 more source

Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress. [PDF]

Front Mol Biosci, 2020
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y.   +11 more
europepmc   +1 more source

Post-translational regulation and evolution of plant gamma-glutamate cysteine ligase

, 2007
Glutamate cysteine ligase (GCL) is catalyzing the rate-limiting step in glutathione (GSH) synthesis. A complex regulation of this enzyme is required to integrate various signals as GSH is fulfilling a plethora of functions in housekeeping metabolism, stress defence, and in the regulation of development.
openaire   +2 more sources

A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato. [PDF]

Adv Sci (Weinh)
Tian X, Li M, Huang X, Wirtz M, Zheng X, Fan S, Tian J, Liu S, Liu Z, Zhao H.   +9 more
europepmc   +1 more source

Glutamate-cysteine ligase as a diagnostic biomarker and therapeutic target in Parkinson's disease: a multi-omics and experimental study. [PDF]

Eur J Med Res
Li X, Wang M, Zhong C, Xia J, Tian L, Wang J, Yang D.   +6 more
europepmc   +1 more source

A genetic variant of the glutamate-cysteine ligase catalytic subunit is associated with susceptibility to ischemic stroke in the Chinese population. [PDF]

Eur J Med Res
Liao T, Weng YH, He J, Chen MR, Chen Y, Qi ZQ, Zhang ZM.   +6 more
europepmc   +1 more source

MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer. [PDF]

EMBO Rep, 2017
Anderton B, Camarda R, Balakrishnan S, Balakrishnan A, Kohnz RA, Lim L, Evason KJ, Momcilovic O, Kruttwig K, Huang Q, Xu G, Nomura DK, Goga A.   +12 more
europepmc   +1 more source

Clinical and Biochemical Analysis of Glutamate-Cysteine Ligase Deficiency Presented with Late-Onset Spinocerebellar Ataxia and Hemolytic Anemia. [PDF]

Mol Syndromol
Al-Hatou M, Safan AS, Atta MA, Siddiqi M.   +3 more
europepmc   +1 more source