Results 191 to 200 of about 585,844 (339)

Tuina Inhibits Synaptic Plasticity Through the Astrocytic NDRG2/GLT-1 Pathway to Alleviate Neuropathic Pain. [PDF]

J Cell Mol Med
Zhang H, Chen L, Jiang J, Huang L, Huang H, Huang L, Chen S, Lin Z.   +7 more
europepmc   +1 more source

How effective are NMDA glutamate receptor antagonists in improving outcomes for patients with stroke and traumatic brain injury (TBI)?

Tripdatabase
openalex   +1 more source

Gulf War Veterans with Psychiatric Symptoms (Anxiety, Depression, and PTSD) Significantly Improve on a Low Glutamate Diet

, 2020
Elizabeth Brandley, Anna E. Kirkland, Kathleen F. Holton   +2 more
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

System Xc-pathway as a potential regulatory target in neurological disorders. [PDF]

Front Pharmacol
Chen Y, Xiao W, Qian C, Huang L, Lv J, Wang Z, Luo Y.   +6 more
europepmc   +1 more source

New plasma diagnostic markers for colorectal cancer: transporter fragments of glutamate tRNA origin [PDF]

Changda Ye, Fu Cheng, Luji Huang, Kang Wang, Lin Zhong, Yan Lü, Manzhao Ouyang   +6 more
openalex   +1 more source

L- [14С] -glutamate uptake by nerve terminals from rat cerebellum and cerebral hemispheres under artificial hypergravity [PDF]

, 2002
Тatiana Borisova, N. Krisanova, N.H. Himmelreich   +2 more
openalex   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Quantitative multi-metabolite imaging of Parkinson's disease using AI boosted molecular MRI. [PDF]

Npj Imaging
Shmuely H, Rivlin M, Perlman O.
europepmc   +1 more source

Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning

Advanced Science, EarlyView.
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao, Guiyuan Shi, Ruixue Qin, Yinghao Sun, Wenbo Guo, Ruixia Shi, Minxian Peng, Jingxuan Yang, Jianjian Zhao, Qiuhan Liu, Jun Xiao, Ke Zhang, Qiang Liu, Wenxing Yang, He Liu   +14 more
wiley   +1 more source