Results 221 to 230 of about 716,780 (343)

Biomimetic Analysis of Neurotransmitters for Disease Diagnosis through Light‐Driven Nanozyme Sensor Array and Machine Learning

Advanced Science, EarlyView.
A novel photoresponsive nanozyme sensor array, combining metal‐organic frameworks (MOFs) with advanced machine learning algorithms, provides a breakthrough in rapid neurotransmitter detection and disease diagnostics. This sensor array is capable of accurately identifying neurotransmitter profiles associated with neurological disorders, offering ...
Kun Yu, Siyuan Lu, Kaiwen Qiu, Yuanzun Zhang, Aobing Sun, Shiqi Gong, Kai Wang, Xuzhu Gao, Xiangyu Xu, Hao Wang   +9 more
wiley   +1 more source

Effects of Bromopyruvate on the Control and Catalytic Properties of Glutamate Dehydrogenase [PDF]

, 1969
J. P. Baker, B. R. Rabin
openalex   +1 more source

Phenylalanine‐Based DNA‐Encoded Chemical Libraries for the Discovery of Potent and Selective Small Organic Ligands Against Markers of Cancer and Immune Cells

Advanced Science, EarlyView.
FM‐DEL1 and FM‐DEL2 are constructed by installing one or two sets of building blocks on a phenylalanine central scaffold. FM‐DELs are screened against markers of prostate, and renal cell carcinoma, and against an immunological target expressed on the surface of natural killer cells.
Francesca Migliorini, Andrea Ciamarone, Sheila Dakhel Plaza, Tony Georgiev, Marta Mascellani, Emanuela Sabato, Giulio Vistoli, Ilaria Biancofiore, Nicholas Favalli, Emanuele Puca, Sebastian Oehler, Dario Neri, Samuele Cazzamalli   +12 more
wiley   +1 more source

Impaired xCT-mediated cystine uptake drives serine and proline metabolic reprogramming and mitochondrial fission in skeletal muscle cells. [PDF]

Redox Biol
Kanaan MN, Karam CY, Kennedy LS, Pileggi CA, Hamilton L, Cuperlovic-Culf M, Harper ME.   +6 more
europepmc   +1 more source

AMINO GROUP FORMATION AND GLUTAMATE SYNTHESIS INSTREPTOCOCCUS BOVIS

, 1964
James J. Burchall, Robert A. Niederman, M. J. Wolin   +2 more
openalex   +1 more source

Glutamate-dehydrogenase inactivation by reduced nicotinamide-adenine dinucleotide phosphate [PDF]

, 1962
Santiago Grisolı́a, Mercedes Fernández, Remi E. Amelunxen, C.L. Quijada   +3 more
openalex   +1 more source

EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy

Advanced Science, EarlyView.
This review provides new perspectives on EGFR's activation, mutations, and their impact on tumor immunotherapy. It summarizes how EGFR is activated and the current EGFR targeting strategy, evaluates their clinical outcomes in combination with immunotherapy, highlighting differential responses in tumors with EGFR wild‐type and different mutants.
Yuanzhuo Gu, Hongchao He, Shilei Qiao, Yifan Shao, Lurong Wang, Zhengkui Zhang, Long Zhang, Fangfang Zhou   +7 more
wiley   +1 more source

Ultrasmall Superparamagnetic Magnetite Nanoparticles as Glutamate-Responsive Magnetic Resonance Sensors. [PDF]

Sensors (Basel)
Mettee H, Asparin A, Ali Z, He S, Li X, Hall J, Kim A, Wu S, Hawker MJ, Uchida M, Wei H.   +10 more
europepmc   +1 more source

The Reversal by Organic Mercurials of “Allosteric” Changes in Glutamate Dehydrogenase

, 1965
Mark W. Bitensky, K. Lemone Yielding, Gordon M. Tomkins   +2 more
openalex   +1 more source

eIF4E Enriched Extracellular Vesicles Induce Immunosuppressive Macrophages through HMGCR‐Mediated Metabolic Rewiring

Advanced Science, EarlyView.
Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal, Minal Nenwani, Ishaque Pulikkal Kadamberi, Sudhir Kumar, Olamide Animasahun, Jasmine George, Shirng‐Wern Tsaih, Prachi Gupta, Mona Singh, Anjali Geethadevi, Chandrima Dey, Noah Meurs, Ajay Shankaran, Pradeep Chaluvally Raghavan, Deepak Nagrath, Sunila Pradeep   +15 more
wiley   +1 more source