Results 281 to 290 of about 898,814 (388)

Localization of neuronal and glial glutamate transporters

Neuron, 1994
J. Rothstein, L. Martin, A. Levey, M. Dykes‐Hoberg, Lin Jin, David Wu, N. Nash, R. Kuncl   +7 more
semanticscholar   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Elevated glioma-related cortical glutamate <i>in vivo</i> is associated with <i>ex vivo</i> interictal discharges in human brain slices. [PDF]

Brain Commun
Jayasekera BAP, Parikh J, Modebadze T, Brito Da Silva A, Stefanetti RJ, Crossman J, Holliman D, Hussain MA, Jenkins A, Major O, Mitchell P, Nicholson C, Ross N, Wallace D, Ward L, Hodgson T, Baker MR, Gorman GS, Blamire A, Cunningham MO, Cowie CJA, LeBeau FEN.   +21 more
europepmc   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Adaptive Gene Expression Induced by a Combination of IL-1β and LPS in Primary Cultures of Mouse Astrocytes. [PDF]

Cells
Coppola T, Poupon G, Rangone H, Martin S, Lebrun P.   +4 more
europepmc   +1 more source

Physiological and metabolic effects of a transposon-mediated mutation in the glutamate synthase gene, gltB, of plant-beneficial, cytokinin-producing Pseudomonas hormoni G20-18T

Ajay M. Sorty, Athanasios Zervas, Vaidotas Kisielius, Chandana Pandey, Rosanna C. Hennessy, Tue Kjærgaard Nielsen, Pedro N. Carvalho, Thomas Roitsch, Peter Stougaard   +8 more
openalex   +1 more source

Glutamate as a neurotransmitter in the brain: review of physiology and pathology.

Journal of NutriLife, 2000
B. Meldrum
semanticscholar   +1 more source

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source

EAR-20 peptide, a novel NMDA receptor positive allosteric modulator. [PDF]

Front Pharmacol
García-Díaz R, Castellanos A, Miguez-Cabello F, Picañol J, Pérez-González AP, Gratacòs-Batlle E, Vega-Castro N, Altafaj X, Reyes-Guzmán EA, Reyes-Montaño EA, Gasull X, Soto D.   +11 more
europepmc   +1 more source

Molecular cloning of the yeast mitochondrial aconitase gene (ACO1) and evidence of a synergistic regulation of expression by glucose plus glutamate.

, 1990
Serge Gangloff, Didier Marguet, Guy J.‐M. Lauquin   +2 more
openalex   +2 more sources