Results 281 to 290 of about 585,844 (339)
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Progress in Neurobiology, 2001
Brain tissue has a remarkable ability to accumulate glutamate. This ability is due to glutamate transporter proteins present in the plasma membranes of both glial cells and neurons. The transporter proteins represent the only (significant) mechanism for removal of glutamate from the extracellular fluid and their importance for the long-term maintenance
N. Danbolt
semanticscholar +3 more sources
Brain tissue has a remarkable ability to accumulate glutamate. This ability is due to glutamate transporter proteins present in the plasma membranes of both glial cells and neurons. The transporter proteins represent the only (significant) mechanism for removal of glutamate from the extracellular fluid and their importance for the long-term maintenance
N. Danbolt
semanticscholar +3 more sources
Neurochemical Research, 2015
Our aim was to review the processes of glutamate release from both biochemical and neurophysiological points of view. A large body of evidence now indicates that glutamate is specifically accumulated into synaptic vesicles, which provides strong support for the concept that glutamate is released from synaptic vesicles and is the major excitatory ...
John T, Hackett, Tetsufumi, Ueda
openaire +2 more sources
Our aim was to review the processes of glutamate release from both biochemical and neurophysiological points of view. A large body of evidence now indicates that glutamate is specifically accumulated into synaptic vesicles, which provides strong support for the concept that glutamate is released from synaptic vesicles and is the major excitatory ...
John T, Hackett, Tetsufumi, Ueda
openaire +2 more sources
Headache Currents, 2004
The NMDA Receptor Antagonist MK‐801 Reduces Fos‐like Immunoreactivity Within the Trigeminocervical Complex Following Superior Sagittal Sinus Stimulation in the Cat Expression of Fos protein is an indicator of neuronal perturbation and is readily observed in the caudal medulla and the spinal cord following trigeminovascular nociceptive
BROMAN J. +4 more
openaire +3 more sources
The NMDA Receptor Antagonist MK‐801 Reduces Fos‐like Immunoreactivity Within the Trigeminocervical Complex Following Superior Sagittal Sinus Stimulation in the Cat Expression of Fos protein is an indicator of neuronal perturbation and is readily observed in the caudal medulla and the spinal cord following trigeminovascular nociceptive
BROMAN J. +4 more
openaire +3 more sources
Glutamate receptors and new glutamate agonists
Trends in Pharmacological Sciences, 1983Abstract A variety of naturally occurring and synthetic analogues of the putative excitatory amino acid neurotransmittersl-glutamic acid (l-GLU) andl-aspartec acid (l-ASP) are powerful neuroexcitatory and neurotoxic agents. These effects appear to be mediated primarily by the central receptors normally operated byl-GLU and/orl-ASP.
Povl Krogsgaard-Larsen, Tage Honore´
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European Neuropsychopharmacology, 2004
Although glutamate is a simple molecule, its actions in the limbic system and areas concerning anxiety are complex and widespread. These actions are mediated through different combinations of ionotropic and metabotropic glutamate receptors. Preclinical studies have shown that compounds active at NMDA, AMPA/kaïnate and metabotropic receptors might have ...
Veerle, Bergink +2 more
openaire +2 more sources
Although glutamate is a simple molecule, its actions in the limbic system and areas concerning anxiety are complex and widespread. These actions are mediated through different combinations of ionotropic and metabotropic glutamate receptors. Preclinical studies have shown that compounds active at NMDA, AMPA/kaïnate and metabotropic receptors might have ...
Veerle, Bergink +2 more
openaire +2 more sources