Results 321 to 330 of about 716,780 (343)
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Glutamate and Glutamate Receptors in the Vertebrate Retina
2023Book chapter published in: Kolb, H., Fernandez, E., Nelson, R., Webvision: The Organization of the Retina and Visual System [Internet].
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2004
Publisher Summary This chapter describes the activity, specificity and structural chemistry of glutamate carboxypeptidase. Glutamate carboxypeptidases are characterized as Zn2+ requiring exopeptidases with specificity for glutamate and this specificity is not absolute as carboxypeptidase G was reported as exhibiting activity against pteroyl compounds ...
Roger F. Sherwood (Deceased) +1 more
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Publisher Summary This chapter describes the activity, specificity and structural chemistry of glutamate carboxypeptidase. Glutamate carboxypeptidases are characterized as Zn2+ requiring exopeptidases with specificity for glutamate and this specificity is not absolute as carboxypeptidase G was reported as exhibiting activity against pteroyl compounds ...
Roger F. Sherwood (Deceased) +1 more
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Localization of glutamate and glutamate transporters in the sensory neurons ofAplysia [PDF]
The Journal of Comparative Neurology, 2000 The sensorimotor synapse of Aplysia has been used extensively to study the cellular and molecular basis for learning and memory. Recent physiologic studies suggest that glutamate may be the excitatory neurotransmitter used by the sensory neurons (Dale and Kandel [1993] Proc Natl Acad Sci USA. 90:7163-7167; Armitage and Siegelbaum [1998] J Neurosci.
Jeannie Chin +5 more
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Enzymatic production of d-glutamate from l-glutamate by a glutamate racemase
Journal of Fermentation and Bioengineering, 1995Abstract d -Glutamate was produced from l -glutamate by two successive cellular reactions with a glutamate racemase produced by Escherichia coli TM93 harboring a plasmid containing a glutamate racemase gene from Lactobacillus brevis ATCC 8287 and a glutamate decarboxylase produced by E. coli ATCC 11246.
Masaki Azuma +3 more
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Glutamate Receptors and Glutamate Corticofugal Pathways
1986Although the neurochemical anatomy of many pathways in human brain has been studied, little attention has been paid to the human pyramidal system. This pathway is very important for voluntary motor control in vertebrates, and pyramidal tract pathology leads to hemiparesis or hemiplegia in primates and man (Phillips and Porter, 1977).
Anne B. Young +3 more
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Neurochemical Research, 1999
In the present study we investigate the effects of a specific glutamate reuptake blocker, L-trans-pyrrolidine-3,4-dicarboxylic acid (PDC), on extracellular concentrations of glutamine and glutamate in the striatum of the freely moving rat. Intracerebral infusions of PDC (1, 2 and 4 mM) produced a dose-related increase in extracellular concentrations of
Francisco Mora +2 more
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In the present study we investigate the effects of a specific glutamate reuptake blocker, L-trans-pyrrolidine-3,4-dicarboxylic acid (PDC), on extracellular concentrations of glutamine and glutamate in the striatum of the freely moving rat. Intracerebral infusions of PDC (1, 2 and 4 mM) produced a dose-related increase in extracellular concentrations of
Francisco Mora +2 more
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Genotoxicity of monosodium glutamate
Food and Chemical Toxicology, 2016Monosodium glutamate (MSG) is one of the most widely used flavor enhancers throughout the world. The aim of this study is to investigate the genotoxic potential of MSG by using chromosome aberrations (CAs), sister-chromatid exchanges (SCEs), cytokinesis-blocked micronucleus (CBMN), and random amplified polymorphic DNA-polimerase chain reaction (RAPD ...
Ataseven, Nazmiye +3 more
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Current Pharmaceutical Design, 2012
Increasing evidence suggests that abnormalities in glutamatergic transmission may be associated with psychosis risk. Genetic polymorphisms associated with schizophrenia converge on NMDA receptor signalling pathways, and transgenic animal models and human neuroimaging studies have shown the functional impact of these risk alleles.
Egerton, Alice +2 more
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Increasing evidence suggests that abnormalities in glutamatergic transmission may be associated with psychosis risk. Genetic polymorphisms associated with schizophrenia converge on NMDA receptor signalling pathways, and transgenic animal models and human neuroimaging studies have shown the functional impact of these risk alleles.
Egerton, Alice +2 more
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2002
The toxic effects of glutamate exposure on neurons were first recognized nearly half a century ago, when Lucas and Newhouse observed that subcutaneous administration of glutamate caused loss of neurons in the inner nuclear layer of the retina in both adult and neonatal mice (1). Olney extended these findings to other regions of brain, including neurons
Dennis W. Choi, B. Joy Snider
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The toxic effects of glutamate exposure on neurons were first recognized nearly half a century ago, when Lucas and Newhouse observed that subcutaneous administration of glutamate caused loss of neurons in the inner nuclear layer of the retina in both adult and neonatal mice (1). Olney extended these findings to other regions of brain, including neurons
Dennis W. Choi, B. Joy Snider
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Hippocampal glutamate receptors
Molecular and Cellular Biochemistry, 1981For years, the hippocampus has been the privileged domain of anatomists and electrophysiologists for investigating various neurobiological processes. The present review deals with recent work which shows that this structure is also well suited to study the role of glutamate as a neurotransmitter and more particularly the characteristics of glutamate ...
Gary Lynch, Michel Baudry
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