Results 331 to 340 of about 898,814 (388)

<i>Panax notoginseng</i> Flower Extract Attenuates Pentylenetetrazole-Induced Epilepsy by Restoring Glutamate Homeostasis. [PDF]

Brain Sci
Zhao Y, Zhu F, Xie J, Wang Y, Matsabisa M, Tang M.   +5 more
europepmc   +1 more source

Therapeutic effects of ginseng and its major components on ischaemic stroke in vitro and in silico. [PDF]

BMC Complement Med Ther
Chen Z, Li L, Liu J, Shen Y, Liu J.
europepmc   +1 more source

Intact corticostriatal function in aged system x_c^- - deficient mice. [PDF]

Transl Psychiatry
De Pauw L, Villers A, Moore C, Lara O, Vanonckelen O, Verbruggen L, Sato H, Bentea E, Arckens L, Ris L, Ates G, Meshul CK, Massie A.   +12 more
europepmc   +1 more source

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Glutamate uptake

Progress in Neurobiology, 2001
Brain tissue has a remarkable ability to accumulate glutamate. This ability is due to glutamate transporter proteins present in the plasma membranes of both glial cells and neurons. The transporter proteins represent the only (significant) mechanism for removal of glutamate from the extracellular fluid and their importance for the long-term maintenance
N. Danbolt
openaire   +3 more sources

The Action of Antidepressants on the Glutamate System: Regulation of Glutamate Release and Glutamate Receptors

Biological Psychiatry, 2013
Recent compelling evidence has suggested that the glutamate system is a primary mediator of psychiatric pathology and also a target for rapid-acting antidepressants. Clinical research in mood and anxiety disorders has shown alterations in levels, clearance, and metabolism of glutamate and consistent volumetric changes in brain areas where glutamate ...
L. Musazzi, G. Treccani, A. Mallei, M. Popoli   +3 more
openaire   +2 more sources

Glutamate and anxiety

European Neuropsychopharmacology, 2004
Although glutamate is a simple molecule, its actions in the limbic system and areas concerning anxiety are complex and widespread. These actions are mediated through different combinations of ionotropic and metabotropic glutamate receptors. Preclinical studies have shown that compounds active at NMDA, AMPA/kaïnate and metabotropic receptors might have ...
Veerle, Bergink, Harold J G M, van Megen, Herman G M, Westenberg   +2 more
openaire   +2 more sources

Glutamate Release

Neurochemical Research, 2015
Our aim was to review the processes of glutamate release from both biochemical and neurophysiological points of view. A large body of evidence now indicates that glutamate is specifically accumulated into synaptic vesicles, which provides strong support for the concept that glutamate is released from synaptic vesicles and is the major excitatory ...
John T, Hackett, Tetsufumi, Ueda
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The Role of Glutamate Transporters in Glutamate Homeostasis in the Brain

Journal of Experimental Biology, 1997
ABSTRACT Glutamate transporters in neurones and glia, four of which have been cloned from mammals, play a crucial role in controlling the extracellular glutamate concentration in the brain. In normal conditions, they remove glutamate from the extracellular space and thereby help to terminate glutamatergic synaptic transmission and to ...
M, Takahashi, B, Billups, D, Rossi, M, Sarantis, M, Hamann, D, Attwell   +5 more
openaire   +2 more sources