Results 91 to 100 of about 56,211 (247)

Neuropharmacological targets for drug action in vestibular sensory pathways [PDF]

open access: yes, 2017
The use of pharmacological agents is often the preferred approach to the management of vestibular dysfunction. In the vestibular sensory pathways, the sensory neuroepithelia are thought to be influenced by a diverse number of neuroactive substances that ...
Jones, Timothy A, Lee, Choongheon
core   +3 more sources

Partial Cloning and Nucleotide Sequencing of Glutamate Decarboxylase Gene Isoform 65 from Human Brain

open access: yesResearch in Molecular Medicine, 2015
Background: Gamma -aminobutyric acid (GABA), a non-protein amino acid acts as an inhibitory neurotransmitter in the central nervous system of mammalians. The glutamate decarboxylase (GAD) is responsible for the conversion of L-glutamate to GABA.
Abolghasem Esmaeili, Maliheh Dehghan
doaj  

High γ-aminobutyric acid production from lactic acid bacteria: emphasis on Lactobacillus brevis as a functional dairy starter [PDF]

open access: yes, 2017
γ-Aminobutyric acid (GABA) and GABA-rich foods have shown anti-hypertensive and anti-depressant activities as the major functions in humans and animals.
Shah, N, Wu, Q
core   +1 more source

Frequency of islet autoantibody seropositivity among adults with newly diagnosed type 2 diabetes in the Kazakh population: A cross‐sectional study

open access: yesJournal of Diabetes Investigation, EarlyView.
Among adults with newly diagnosed type 2 diabetes in Kazakhstan, 25.8% showed islet autoantibody positivity, indicating a substantial autoimmune component. ZnT8 and GADA were the most prevalent, supporting the importance of immunological assessment for accurate diabetes classification.
Khatimya Kudabayeva   +3 more
wiley   +1 more source

Establishment of a Stable Glutamate Decarboxylase (Gad) Expressing Cell-Line by Transfection

open access: yesCell Transplantation, 1993
We have constructed a recombinant DNA clone containing the gene encoding glutamic acid decarboxylase (GAD), which catalyzes the synthesis of γ-amino-butyric acid (GABA).
Feng C. Zhou   +2 more
doaj   +1 more source

A novel approach in acidic disinfection through inhibition of acid resistance mechanisms; Maleic acid-mediated inhibition of glutamate decarboxylase activity enhances acid sensitivity of Listeria monocytogenes [PDF]

open access: yes, 2018
Here it is demonstrated a novel approach in disinfection regimes where specific molecular acid resistance systems are inhibited aiming to eliminate microorganisms under acidic conditions. Despite the importance of the Glutamate Decarboxylase (GAD) system
Barnes, Ruth H.   +2 more
core   +1 more source

The multidimensional regulation roles and mechanisms of calcium in fruit quality

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review explores how calcium signaling molecule integrates plant hormones, environmental cues, and developmental signals to influence external fruit traits, internal nutritional properties, and physiological disorders. ABSTRACT Calcium (Ca2+), a dual‐functional mineral that serves both as an essential structural factor and a signaling molecule ...
Fei Jiang   +6 more
wiley   +1 more source

Screening of 31 Lactic Acid Bacteria Strains Identified Levilactobacillus brevis NCTC 13768 as a High-Yield GABA Producer

open access: yesApplied Sciences
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the vertebrate central nervous system, known for its role in promoting sleep, reducing anxiety, regulating blood pressure, and modulating stress, cognition, and behavior. Microbial
Desislava Teneva   +10 more
doaj   +1 more source

Serotonin system implication in L-DOPA-induced dyskinesia: from animal models to clinical investigations [PDF]

open access: yes, 2014
In the recent years, the serotonin system has emerged as a key player in the induction of l-DOPA-induced dyskinesia (LID) in animal models of Parkinson's disease. In fact, serotonin neurons possess the enzymatic machinery able to convert exogenous l-DOPA
CARTA, MANOLO, TRONCI, ELISABETTA
core   +1 more source

Guard cell photorespiration controls stomata behavior and development

open access: yesNew Phytologist, EarlyView.
Summary Photorespiration is traditionally viewed as a limitation to photosynthetic efficiency. However, it is mandatory for safeguarding the Calvin–Benson–Bassham cycle from inhibitory byproducts through Rubisco‐mediated oxidative misfire and is tightly integrated with primary metabolism.
Hu Sun   +6 more
wiley   +1 more source

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