Neuropharmacological targets for drug action in vestibular sensory pathways [PDF]
The use of pharmacological agents is often the preferred approach to the management of vestibular dysfunction. In the vestibular sensory pathways, the sensory neuroepithelia are thought to be influenced by a diverse number of neuroactive substances that ...
Jones, Timothy A, Lee, Choongheon
core +3 more sources
Background: Gamma -aminobutyric acid (GABA), a non-protein amino acid acts as an inhibitory neurotransmitter in the central nervous system of mammalians. The glutamate decarboxylase (GAD) is responsible for the conversion of L-glutamate to GABA.
Abolghasem Esmaeili, Maliheh Dehghan
doaj
High γ-aminobutyric acid production from lactic acid bacteria: emphasis on Lactobacillus brevis as a functional dairy starter [PDF]
γ-Aminobutyric acid (GABA) and GABA-rich foods have shown anti-hypertensive and anti-depressant activities as the major functions in humans and animals.
Shah, N, Wu, Q
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Among adults with newly diagnosed type 2 diabetes in Kazakhstan, 25.8% showed islet autoantibody positivity, indicating a substantial autoimmune component. ZnT8 and GADA were the most prevalent, supporting the importance of immunological assessment for accurate diabetes classification.
Khatimya Kudabayeva +3 more
wiley +1 more source
Establishment of a Stable Glutamate Decarboxylase (Gad) Expressing Cell-Line by Transfection
We have constructed a recombinant DNA clone containing the gene encoding glutamic acid decarboxylase (GAD), which catalyzes the synthesis of γ-amino-butyric acid (GABA).
Feng C. Zhou +2 more
doaj +1 more source
A novel approach in acidic disinfection through inhibition of acid resistance mechanisms; Maleic acid-mediated inhibition of glutamate decarboxylase activity enhances acid sensitivity of Listeria monocytogenes [PDF]
Here it is demonstrated a novel approach in disinfection regimes where specific molecular acid resistance systems are inhibited aiming to eliminate microorganisms under acidic conditions. Despite the importance of the Glutamate Decarboxylase (GAD) system
Barnes, Ruth H. +2 more
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The multidimensional regulation roles and mechanisms of calcium in fruit quality
This review explores how calcium signaling molecule integrates plant hormones, environmental cues, and developmental signals to influence external fruit traits, internal nutritional properties, and physiological disorders. ABSTRACT Calcium (Ca2+), a dual‐functional mineral that serves both as an essential structural factor and a signaling molecule ...
Fei Jiang +6 more
wiley +1 more source
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the vertebrate central nervous system, known for its role in promoting sleep, reducing anxiety, regulating blood pressure, and modulating stress, cognition, and behavior. Microbial
Desislava Teneva +10 more
doaj +1 more source
Serotonin system implication in L-DOPA-induced dyskinesia: from animal models to clinical investigations [PDF]
In the recent years, the serotonin system has emerged as a key player in the induction of l-DOPA-induced dyskinesia (LID) in animal models of Parkinson's disease. In fact, serotonin neurons possess the enzymatic machinery able to convert exogenous l-DOPA
CARTA, MANOLO, TRONCI, ELISABETTA
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Guard cell photorespiration controls stomata behavior and development
Summary Photorespiration is traditionally viewed as a limitation to photosynthetic efficiency. However, it is mandatory for safeguarding the Calvin–Benson–Bassham cycle from inhibitory byproducts through Rubisco‐mediated oxidative misfire and is tightly integrated with primary metabolism.
Hu Sun +6 more
wiley +1 more source

