Results 121 to 130 of about 228,854 (227)

A Pathway‐Based Metabolomics Approach Reveals Metabolic Strategies and Reprogramming in Drought‐Tolerant Soybean Genotypes

Legume Science, Volume 8, Issue 1, March 2026.
ABSTRACT Soybean (Glycine max) is a globally important crop, yet its productivity is highly susceptible to drought stress, particularly in rainfed systems. To better understand the biochemical basis of drought tolerance, this study employed pathway‐based metabolomics to characterize differentially expressed metabolites between drought‐tolerant and ...
Namhee Lee, Donna K. Harris, Zenglu Li, Joon Hyuk Suh   +3 more
wiley   +1 more source

Peptide Antibody Reactivity to Homologous Regions in Glutamate Decarboxylase Isoforms and Coxsackievirus B4 P2C. [PDF]

Int J Mol Sci, 2022
Trier NH, Valdarnini N, Fanelli I, Rovero P, Hansen PR, Schafer-Nielsen C, Ciplys E, Slibinskas R, Pociot F, Friis T, Houen G.   +10 more
europepmc   +1 more source

Dual mechanisms regulating glutamate decarboxylases and accumulation of gamma-aminobutyric acid in tea (Camellia sinensis) leaves exposed to multiple stresses [PDF]

, 2016
Xin Mei, Yiyong Chen, Lingyun Zhang, Xiumin Fu, Qing Wei, Don Grierson, Ying Zhou, Yahui Huang, Fang Dong, Ziyin Yang   +9 more
openalex   +1 more source

Disruption of the l‐DOPA Receptor Gpr143/OA1‐Gene in Mice Creates a Unique Mixed Psychosis‐Like Phenotype

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima, Haruko Nakamura, Motokazu Koga, Junka Koyama, Yayoi Kimura, Maya N. Vasishth, Evan Y. Snyder, Masashi Asai, Kenta Sakai, Daiki Masukawa   +9 more
wiley   +1 more source

Evaluation of GABAergic and Glutamatergic Levels in the Dorsal Anterior Cingulate Cortex of Patients With Bipolar Disorder: A Cross‐Sectional 1H‐MRS Study

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
Using 1H‐MRS with MEGA‐PRESS, we found no significant differences in dACC GABA or Glx levels between bipolar disorder patients and controls. However, GABA levels were higher in lithium‐treated patients, suggesting medication effects on GABAergic tone. ABSTRACT Background Imbalances between excitatory and inhibitory (E/I) neurotransmitters in the brain ...
Sotaro Moriyama, Yoshihiro Noda, Shiori Honda, Richard A. E. Edden, Koki Takahashi, Keisuke Saito, Keita Taniguchi, Masataka Wada, Sakiko Tsugawa, Yui Tobari, Sunjun Huh, Yumina Nakane, Saki Homma, Mie Matsui, Shinsuke Koike, Masaru Mimura, Hiroyuki Uchida, Shinichiro Nakajima   +17 more
wiley   +1 more source

Characterization of a novel glutamate decarboxylase (GAD) from Latilactobacillus curvatus K285 isolated from Gat -Kimchi. [PDF]

Food Sci Biotechnol, 2022
Lee SJ, Jeon HS, Yoo JY, Kang YJ, Kim MJ, Kim TJ, Kim JH.   +6 more
europepmc   +1 more source

Characterization of the Gamma-Aminobutyric Acid (GABA) Biosynthetic Gene Cluster in High GABA-Producing Enterococcus avium G-15

Fermentation
We have previously shown that the lactic acid bacterium (LAB) Enterococcus avium G-15 produces gamma-aminobutyric acid (GABA) from monosodium l-glutamate (Glu) at a hyper conversion rate.
Masafumi Noda, Moeko Ozaki, Saori Ogura, Narandalai Danshiitsoodol, Etsuji Nakashima, Masanori Sugiyama   +5 more
doaj   +1 more source

Development of a Continuous, Uncoupled Fluorescence‐based Assay for Monitoring Methyltransferase Activity: Methylation Going Sour

ChemCatChem, Volume 18, Issue 3, 12 February 2026.
Methylation going sour: The first uncoupled fluorescence‐based assay was established to measure methyltransferase activity in a continuous fashion. Different use cases are presented, including the assay's compatibility with catalyst formulations other than purified enzymes, the determination of kinetic parameters, as well as the screening of a ...
Benjamin Panagiotis Chapple, Lisa M. Böhmer, Jörg Pietruszka   +2 more
wiley   +1 more source

Table S2 from Glutamate Decarboxylase 65 Signals through the Androgen Receptor to Promote Castration Resistance in Prostate Cancer

, 2023
Yi Qin Gao, Lü Chen, Zunguo Du, WenChao Gao, ZhengMing Wu, Xiujuan Liu, Hai Huang, Danfeng Xu, Qingquan Li   +8 more
openalex   +1 more source

Ablation of Unilateral Hippocampal GABAergic Neurons: A Novel Mouse Model of Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
A novel mouse model of mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS) by unilateral, partial ablation of hippocampal GABAergic neurons is established. The model recapitulates key features of the human condition, including spontaneous recurrent seizures, HS‐like pathology, and associated cognitive deficits.
Ting Tang, Jinkun Xu, Bin Fu, Chao Geng, Yuhao Li, Yuying Qi, Changkai Hou, Junping He, Yihe Wang, Yumin Luo, Guoguang Zhao   +10 more
wiley   +1 more source