Effect of different salt concentrations on the gamma-aminobutyric-acid content and glutamate decarboxylase activity in germinated sorghum (Sorghum bicolor L. Moench) grain. [PDF]
Elbaloula MF, Hassan AB.
europepmc +1 more source
Atractylone exhibits diverse pharmacological effects, including anticancer and neuroprotection. A systematic review was conducted following PRISMA guidelines to analyze Atractylone. This study explores Atractylone's sources, biosynthesis, and therapeutic potential.
Hamza Elhrech +8 more
wiley +1 more source
Cannabinoid Receptor Type 1 Regulates Drug Reward Behavior via Glutamate Decarboxylase 67 Transcription. [PDF]
Gu SM +10 more
europepmc +1 more source
Substrate specificity of a ketosynthase domain involved in bacillaene biosynthesis
An isotopic labelling method was developed to investigate substrate binding by ketosynthases, exemplified by the second ketosynthase of the polyketide synthase BaeJ involved in bacillaene biosynthesis (BaeJ-KS2).
Zhiyong Yin, Jeroen S. Dickschat
doaj +1 more source
Molecular cloning and amino acid sequence of brain L-glutamate decarboxylase.
W M Huang +3 more
openalex +2 more sources
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Oral Supplementation With a Bovine Thymus Extract Reduces Neuronal Excitability in Aging Mice
Oral supplementation of aging mice with a nuclear fraction extract of bovine thymus (TNF) leads to significant increases in GAD65, GAD67, and β2/β3 subunits of the GABAA receptor, more so with high dose (HD) TNF treatment compared to low dose (LD) and control condition.
Abdeslem El‐Idrissi +2 more
wiley +1 more source
Impact of Dysfunctional Feed-Forward Inhibition on Glutamate Decarboxylase Isoforms and γ-Aminobutyric Acid Transporters. [PDF]
Panthi S, Lyons NMA, Leitch B.
europepmc +1 more source
Lifespan‐Extending Endogenous Metabolites
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley +1 more source
Weak Association Between the Glutamate Decarboxylase 1 Gene (GAD1) and Schizophrenia in Han Chinese Population. [PDF]
Zhang L +14 more
europepmc +1 more source

